Protein Alignment ppk7 and Asic2

DIOPT Version :10

• Sequence 1: NP_609016.2
• Gene: ppk7 / 33886
• FlyBaseID: FBgn0031802
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 536
• Identity: 128/536 - (23%)
• Similarity: 197/536 - (36%)
• Gaps: 150/536 - (27%)

  Fly    41 RTTIHGLDRL----LSAKASRWERFVWLCTFVSAFLGAVYVCLILSARYN-AAHFQTVVDSTRFP 100
            ||.:|||..:    .:|..|...|.:|:..|.:: ||     |:||...| ..::.:....||
Mouse    63 RTKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTS-LG-----LLLSWSSNRLLYWLSFPSHTR-- 119

  Fly   101 VYR-----IPFPVITICNRNRLNWQRLAEAKSRF------LANGSNSAQQELFELIVG------- 147
            |:|     :|||.:|:||.|.|.:.||::....:      |...:.:|:..:.||:.|
Mouse   120 VHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQW 184

  Fly   148 ---TYDDAYF---GHFQS-----FERLRNQPTELL---NY-------VNFSQV---------VDF 182
               ..|...|   .||:.     .:||.:|..::|   .|       .|||.|         .|.
Mouse   185 FRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVSCPPREPALSDP 249

  Fly   183 MTWRCNELLAECLWRHHAYDCCEIFSKRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGP 247
            ...|..|.|.   |.........:|    :|.|.|:.|||  .|:|:      |:.....|..|
Mouse   250 ALPRSPEALR---WAPGTGHQAPVF----TKYGKCYMFNS--GEDGK------PLLTTVKGGTG- 298

  Fly   248 MSALSVRVLIQPAKH---WPGHRETNAMKGIDVMV---TEPFVWHNNPFFVAANTETTMEIEPVI 306
             :.|.:.:.||..::   |....||....|:.|.:   :||.......|.||...:|.:..:...
Mouse   299 -NGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQR 362

  Fly   307 YFYDNDTRG-VRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTM-----D 365
            ..|.....| .||.:.         ..||..    ||.|..|:.:|...|:|..|||.|     |
Mouse   363 LTYLPPPWGECRSSEM---------GLDFFP----VYSITACRIDCETRYIVENCNCRMVHMPGD 414

  Fly   366 LLF-PPGQYRSCRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMSCKCFRNCYSLNYISDVRP 429
            ..| .|.|::.|....|..|||.:                    ...|.|...|....|..::..
Mouse   415 APFCTPEQHKECAEPALGLLAEKD--------------------SNYCLCRTPCNLTRYNKELSM 459

  Fly   430 AFLP--------------PDVYANNSYVDLDVHF---RFETI---MVYRTSLVFGWVDLMVSFGG 474
            ..:|              .:.|.:.:.:.||:.|   .:|||   ..|..:.:.|      ..||
Mouse   460 VKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLG------DIGG 518

  Fly   475 IAGLFLGCSLISGMEL 490
            ..|||:|.|:::.:||
Mouse   519 QMGLFIGASILTILEL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk7	NP_609016.2	ASC	38..493	CDD:459966	128/536 (24%)
Asic2	XP_006532059.1	ENaC	64..590	CDD:273304	127/535 (24%)