DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9498 and CG31300

DIOPT Version :9

Sequence 1:	NP_609015.2	Gene:	CG9498 / 33885	FlyBaseID:	FBgn0031801	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_651373.2	Gene:	CG31300 / 326132	FlyBaseID:	FBgn0051300	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	119/446 - (26%)
Similarity:	191/446 - (42%)	Gaps:	67/446 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NEQNISVPEYLNEHFFTETLE--EGLRESKVTLKEINFAWGSNPGDNYCSAIYRVGV-------S 61
            |:..:..|.:||..|..|.|.  |...|.||.  ::.....|..||:|.|.::|...       .
  Fly    11 NDDELEAPAWLNRQFIEEILSAYEDSPELKVV--DLKITPASAQGDHYASVMFRTTAECTTAKGK 73

  Fly    62 FARWADGGESPVTEQLSLIVKTIPITEA--TQFLEDVCVFIKEKQTYTDVLPRLDILSR--GD-- 120
            |:|             .||:|.:|..:.  ...|.:..:|..|...|..|||..:.:.|  ||
  Fly    74 FSR-------------PLIIKAMPEQDGHKKDMLSESHLFETEIGMYCQVLPEFERILRESGDDT 125

  Fly   121 -TFGAKYYHSVKTPVQTIVFSDLTVEGFKVASREKGLDWNHASLILQQLGKFHATSMVLAKKDPA 184
             .|....|||:: |.:.::|.||..:|:.|. |::.:..........:|.|:||.||...|:.|.
  Fly   126 KLFVPCIYHSLE-PRKVMIFEDLVPQGYYVI-RDRPVAQEELKTAFAKLAKWHAISMKYIKEQPD 188

  Fly   185 IVKQYTRGMLSEDILMKSDTF----EQMFGGFLKGLIKSSASWAGYEKI-SKHLQRLMDNFRNVC 244
            .:|::..| |.|...:|:|.|    .|.|...|..|.:.......:||| .|::|||    :.|.
  Fly   189 FLKEFKYG-LFEMPTVKTDPFITTGMQSFIEMLDRLPELRKYKPHFEKIKDKYMQRL----QAVM 248

  Fly   245 ADAPRPRKGDRYVVLNHGDLWTNNFMYGYDNASQPDVPTRAIFVDFQLSFYGSPACDLNFFLNTS 309
            .:....||.|.:.||.|||....|.|:..:..:.....|  :.||||:    |..|.:...|..|
  Fly   249 KEYHENRKSDAFYVLCHGDFHLRNMMFKNNKGTGAHEDT--MLVDFQI----SNLCPITIDLTYS 307

  Fly   310 IKLQLLQERREEL--------IKVYYASFKDALEYARFEDIPSYEDLQYELRSRETYGLFGMFAF 366
            |.:.:..|:|.|:        :.|..|:.| ::.|.  .::|:...|..|:...:.|..|.:..|
  Fly   308 IYMLMEPEQRREMGKDLINHYLTVLVATLK-SIGYP--GELPTQAKLWDEIHKNKYYDFFLLSTF 369

  Fly   367 LPMITMPKELA-QDNSIENMQDEAFKQRKMDAIFSQKFLNDHQKWALKRADSLGVF 421
            ||:|...|..: :.|.:  :||...:|:   ..|...::.|..| .|.:.:.||.|
  Fly   370 LPLILAIKSKSFKVNDL--IQDPETRQK---TYFLDTYVKDVSK-LLPKFEQLGYF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9498	NP_609015.2	EcKinase	47..339	CDD:281023	86/318 (27%)
CG31300	NP_651373.2	EcKinase	52..341	CDD:281023	85/315 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850