DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9498 and CG33301

DIOPT Version :9

Sequence 1:	NP_609015.2	Gene:	CG9498 / 33885	FlyBaseID:	FBgn0031801	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001285793.1	Gene:	CG33301 / 2768917	FlyBaseID:	FBgn0053301	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	106/430 - (24%)
Similarity:	182/430 - (42%)	Gaps:	57/430 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VPEYLNEHFFTETLEEGLRESKVTLKEINFAWGSNPGDNYCSAIYRVGVSFARWADGGESPVTEQ 76
            :|.:|...:....|....::.::.:..|.....:..|:|:...:.|:.|.:..    |:..|..:
  Fly     2 LPTWLTAAYLQPRLRAYCQDDRLQVLRIWAKPATGKGENFVGVMTRIYVDYQL----GDGSVVNK 62

  Fly    77 LSLIVKTI--PITEATQFLEDVCVFIKEKQTYTDVLPRLDILSRGDTFGAKYYH---SVKTPVQT 136
            ..::.:.:  .:.:|..|.| ..::.:|...|..:||:|..|.:......|...   :|.....|
  Fly    63 TYIVKQALSAEVPQAEVFFE-YELYTREMDMYEFILPKLKELLQEAGLDQKLTADAITVDREYNT 126

  Fly   137 IVFSDLTVEGFKVASREKGLDWNHASLILQQLGKFHATSMVLAKKDPAIVKQ--YTRGMLSEDIL 199
            ::..||....|..|.|.|.||..|..|.|:.|.||||.|:||.::.|.::.:  ||. ..|.|..
  Fly   127 MILEDLAPYKFVNADRVKQLDMAHTELTLEMLAKFHAASIVLQERHPNLLTKCFYTH-FFSRDKK 190

  Fly   200 MKSDTFEQMFGGFLKGL-----IKSSASWAGYEKISKHLQRLMDNFRNVCADAPRPRKGDRYVVL 259
            ..|..|..:|..||:.:     :|        |.....|.:|..:.....|.|....:.| ...|
  Fly   191 AYSVVFAGLFKAFLRFIDGQPNLK--------EAYGDKLHKLRTHIMEYGARAYDVGESD-LKTL 246

  Fly   260 NHGDLWTNNFMYGYDNASQPDVPTRAIFVDFQLSFYGSPACDLNFFLNTSIKLQLLQERREELIK 324
            ||||.||.|.|:.||:|.:   |...:.:|||.|...||..||::|..||:: :.:.::..||::
  Fly   247 NHGDCWTTNIMFQYDDAGE---PRSVVAIDFQFSNCTSPTIDLHYFFTTSLR-EEVGDKESELVE 307

  Fly   325 VYYASFKDALEYARFE-DIPSYED--LQYELR------------------SRETYGLFGMFAFLP 368
            .:|.:.|..||...:: .:|:.::  ||:|.|                  |.||.....::|
  Fly   308 HHYKALKANLEKFSYKGSLPTLQEYRLQFERRRFMSLLAHMFKPCMIYNGSEETSDFSSLYA--- 369

  Fly   369 MITMPKELAQDNSIENMQDEAFKQRKMDAIFSQKFLNDHQ 408
              ..|:.|....|:...:.......|:.||...|.|.:.|
  Fly   370 --ESPEGLRYQKSVYASEAVIRSATKLLAILDAKGLLELQ 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9498	NP_609015.2	EcKinase	47..339	CDD:281023	84/303 (28%)
CG33301	NP_001285793.1	EcKinase	37..322	CDD:281023	84/303 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459176
Domainoid	1	1.000	62	1.000	Domainoid score	I6837
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25766
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	9	8.860