Protein Alignment Cpr and NCP1

DIOPT Version :9

• Sequence 1: NP_001260128.1
• Gene: Cpr / 33883
• FlyBaseID: FBgn0015623
• Length: 679
• Species: Drosophila melanogaster
• Sequence 2: NP_011908.1
• Gene: NCP1 / 856438
• SGDID: S000001084
• Length: 691
• Species: Saccharomyces cerevisiae
• Alignment Length: 704
• Identity: 240/704 - (34%)
• Similarity: 362/704 - (51%)
• Gaps: 73/704 - (10%)

  Fly    27 DVALLAVLIGGAAFYFLRSRKKEEEPTRSYSIQPTTVCTTSASDNSFIKKLKASGRSLVVFYGSQ 91
            |..:||.|:.....|..|:..||     ........:...|:.:....:.:..:.::.:|.|.||
Yeast     9 DFTVLAGLVLAVLLYVKRNSIKE-----LLMSDDGDITAVSSGNRDIAQVVTENNKNYLVLYASQ 68

  Fly    92 TGTGEEFAGRLAKEGI-RYRLKGMVADPEECDMEELLQLKDIDNSLAVFCLATYGEGDPTDNAME 155
            |||.|::|.:.:||.: ::.|..|.||.|..|.|   .|.|:...:::| ::||||||..|.|:.
Yeast    69 TGTAEDYAKKFSKELVAKFNLNVMCADVENYDFE---SLNDVPVIVSIF-ISTYGEGDFPDGAVN 129

  Fly   156 FYEWITSGDVD-LSGLNYAVFGLGNKTYEHYNKVAIYVDKRLEELGANRVFELGLGDDDANIED- 218
            |.::|.:.:.. ||.|.|.:|||||.|||.:|..|...:|.|...||.|:.:||..||.|...|
Yeast   130 FEDFICNAEAGALSNLRYNMFGLGNSTYEFFNGAAKKAEKHLSAAGAIRLGKLGEADDGAGTTDE 194

  Fly   219 DFITWKDRFWPAVCDHFGIEGGGEEVLIR-QYRLLEQPDVQPDRIYTGEIAR----LHSIQN--- 275
            |::.|||.....:.|...::....:...: ||.:|.:   ..|.:..||.:.    .|.:..
Yeast   195 DYMAWKDSILEVLKDELHLDEQEAKFTSQFQYTVLNE---ITDSMSLGEPSAHYLPSHQLNRNAD 256

  Fly   276 --QRPPFDAKNPFLAPIKVNRELHKGGGRSCMHIELSIEGSKMRYDAGDHVAMFPVNDKSLVEKL 338
              |..|||...|::|||..:|||.....|:|:|.|..:.||.::|..|||:|::|.|....||:.
Yeast   257 GIQLGPFDLSQPYIAPIVKSRELFSSNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQF 321

  Fly   339 GQLCNADLDTVFSLINTDTDSSKKHPFPCPTTYRTALTHYLEITAIPRTHILKELAEYC--TDEK 401
            ..:.|.|.:|:|.|  ...|.:.|.|||.|||...|:.||||||......:...|.::.  .|.|
Yeast   322 LSIFNLDPETIFDL--KPLDPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVK 384

  Fly   402 EKELL--RSMASISPEGKEKYQSWIQDACRNIVHILEDIKSCRPPIDHVCELLPRLQPRYYSISS 464
            ||..|  :.....:.|...||.: |.||.:   ::.:..|....|:..:.|.:|::.||||||||
Yeast   385 EKLTLLSKDKDQFAVEITSKYFN-IADALK---YLSDGAKWDTVPMQFLVESVPQMTPRYYSISS 445

  Fly   465 SAKLHPTDVHVTAVLVEY---KTPTGRINKGVATTYLKNKQ-PQGSEEV---------------- 509
            |:......||||:::..:   :.|......||.|..|:|.| .|.:..:
Yeast   446 SSLSEKQTVHVTSIVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGPRK 510

  Fly   510 -----KVPVFIRKSQFRLPTKPETPIIMVGPGTGLAPFRGFIQER-QFLRDEGK-----TVGESI 563
                 |:||.:|:|.||||:.|.||:||:|||||:|||||||:|| .||..:.|     ::|:.|
Yeast   511 LFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNNVSLGKHI 575

  Fly   564 LYFGCRKRSEDYIYESELEEWVKK--GTLNLKAAFSR-DQGKKVYVQHLLEQDADLIWNVIGENK 625
            |::|.| .::|::|:.|..|:.||  |:..:..|.|| ...||||||..|:...|.::.:|  |.
Yeast   576 LFYGSR-NTDDFLYQDEWPEYAKKLDGSFEMVVAHSRLPNTKKVYVQDKLKDYEDQVFEMI--NN 637

  Fly   626 GHF-YICGDAKNMAVDVRNILVKILSTKGNMSEADAVQYIKKMEAQKRYSADVW 678
            |.| |:|||||.||..|...||.|||...:::..:|.:.||.::...||..|||
Yeast   638 GAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKTSGRYQEDVW 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpr	NP_001260128.1	CysJ	80..678	CDD:223446	229/649 (35%)
		Flavodoxin_1	86..223	CDD:278677	57/139 (41%)
		CYPOR	281..678	CDD:99801	158/435 (36%)
NCP1	NP_011908.1	Flavodoxin_1	63..199	CDD:395199	57/139 (41%)
		CYPOR	264..691	CDD:99801	158/435 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345628
Domainoid	1	1.000	127	1.000	Domainoid score	I1172
eggNOG	1	0.900	-	-		E1_COG0369
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H725
Inparanoid	1	1.050	337	1.000	Inparanoid score	I417
Isobase	1	0.950	-	0.959148	Normalized mean entropy	S1154
OMA	1	1.010	-	-		QHG53742
OrthoFinder	1	1.000	-	-		FOG0001018
OrthoInspector	1	1.000	-	-		oto99076
orthoMCL	1	0.900	-	-		OOG6_100886
Panther	1	1.100	-	-	LDO	PTHR19384
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R800
SonicParanoid	1	1.000	-	-		X2066
TreeFam	1	0.960	-	-
	16	15.740