Protein Alignment Pez and PTPRH

DIOPT Version :10

• Sequence 1: NP_609013.1
• Gene: Pez / 33882
• FlyBaseID: FBgn0031799
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_016882545.1
• Gene: PTPRH / 5794
• HGNCID: 9672
• Length: 1137
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 81/299 - (27%)
• Similarity: 123/299 - (41%)
• Gaps: 45/299 - (15%)

  Fly   967 KDKLCQILD--QKL-----SDSQLFMEFERIPKRREHALYECALLEENEPKNHDPNFLPYDDNRV 1024
            :|..|...|  |:|     |.||:                 .|...||..||...|.||||.:||
Human   836 RDSNCGFADEYQQLSLVGHSQSQM-----------------VASASENNAKNRYRNVLPYDWSRV 883

  Fly  1025 RLTPCRDN-RHGYVNASSISATVGTKQRFYIVAQSPQEPLTMRIFWQCVWEADVYLVVQLTEDMS 1088
            .|.|..:. ...|:|||.:......::  :|..|.|. |.|:..||:.|||...:.:|.||..|.
Human   884 PLKPIHEEPGSDYINASFMPGLWSPQE--FIATQGPL-PQTVGDFWRLVWEQQSHTLVMLTNCME 945

  Fly  1089 --------YIPRNSHQRLEFGQFQVYQEFSQTTDRCTTIKLRLYHVPSRRYRSVWYLQYADWAEQ 1145
                    |.|.:| |....|..:|.....:..:..|..:|.|..|..::..||....|..|.:.
Human   946 AGRVKCEHYWPLDS-QPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDH 1009

  Fly  1146 NCPRDVNHFLDFLEELNSVRLASTQEVPPGHNTNPPVLLHCLEGGGRSGVTLTADLLLYTLDHNE 1210
            ..|...:..|.|...|.. .|..|.|      ..||: :||..|.||:|..:..|:||..|....
Human  1010 GVPSSPDTLLAFWRMLRQ-WLDQTME------GGPPI-VHCSAGVGRTGTLIALDVLLRQLQSEG 1066

  Fly  1211 DLDIPRVIGQLRHQRDSIIPSLAQYKFIYNLLITYLKRT 1249
            .|.....:.::|..|..::.:.|||.|::..::.:|:::
Human  1067 LLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQS 1105

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pez	NP_609013.1	FERM_F1_PTPN14_like	17..107	CDD:340619
		FERM_M	112..230	CDD:459788
		FERM_C_PTPN14_PTPN21	225..317	CDD:270009
		PTP_DSP_cys	1036..1246	CDD:475123	58/217 (27%)
PTPRH	XP_016882545.1	FN3	52..139	CDD:238020
		FN3	141..228	CDD:238020
		FN3	231..314	CDD:238020
		FN3	285..>709	CDD:442628
		R-PTPc-H	870..1102	CDD:350467	68/243 (28%)