Protein Alignment Pez and Ptp52F

DIOPT Version :10

• Sequence 1: NP_609013.1
• Gene: Pez / 33882
• FlyBaseID: FBgn0031799
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Alignment Length: 1160
• Identity: 215/1160 - (18%)
• Similarity: 370/1160 - (31%)
• Gaps: 367/1160 - (31%)

  Fly   227 EERFAAKDTLGNDLLLGLAINGMVVNADNGRQYFPWKEFHTVTIDKRTIKIEQNKLDGGGSIVGS 291
            ||.||..|.|..   .|:.:..:|.|..||.....::|..||..|:.::            |...
  Fly   404 EETFAIFDDLDP---CGIYLVEIVPNQLNGSAGTKYQEQSTVGEDQPSV------------IQDP 453

  Fly   292 FIFSEADTARYFWKLTISQHKFFKRYIDTATPSSLGSGADAESGPLGVDSV---GYVDYDYNEAA 353
            .:.:||.:....||                ||         |...|.:|..   |:::.|
  Fly   454 VVEAEAYSMEVSWK----------------TP---------EYADLCIDGYRLSGWMEDD----- 488

  Fly   354 AAEQLQQHHQQQQHMQQQQQIQQQQMISSNISLATSANQMLGQ--SSSCLDLSNNNLHSSSGMLH 416
                            :..:::...:.:.|.::....|.:..|  ....:..:..||   .|.|.
  Fly   489 ----------------KLVEVEALSITTQNTTVVFDKNLLACQVYIIQIIPYTKENL---DGQLR 534

  Fly   417 HGGSNNNNNNDERERLKAMLPTYRPAPDYETAVQLKYRTPSAEFHNVALAMAAPGNAYYAGSQP- 480
            ..|...          ||.:..|       |.|:|:.:...:||.:: :|.    ||.|..|.|
  Fly   535 QVGVET----------KAAIVDY-------TKVKLEMKNAGSEFIDL-IAF----NADYNNSCPT 577

  Fly   481 -----------DVHNPGMHNENLLYGH---------------------MTAHRYPDVAQPAAALH 513
                       .|.||  :.|..:.||                     :..:.....::|.....
  Fly   578 IFALFTCNATTQVRNP--YAERYVEGHSKQGFNASLSPLSPYATYVCKVILYNVAGPSEPVVDAD 640

  Fly   514 HHINLYQAQHQPQSHPQPMSPAQAYLELSQRMHMMRHKAPPPYVN------------RLSSSSTP 566
            .|...|          .|..|....||.|....::.:..||.|.|            ..:|...|
  Fly   641 MHTTTY----------FPEQPESVMLEKSTVSSLLFNWQPPTYTNGPIKYYQAFLMRHEASYFVP 695

  Fly   567 -DLAVATPRPLQGFRNYVSGSSPDLVSNRTLFNGGQYVALPAGGHAGNIPTSSGATMLHQYQYVS 630
             |.|:..    |..::...|.                   |:....|..|     .:.:..|..:
  Fly   696 ADCAIVE----QDTKSETKGD-------------------PSVNFTGLAP-----AVRYMMQVAA 732

  Fly   631 H----MG-HSQPYLPPHGTFENLNMIEEQPSIMSQLRQSAMSQAAAAAAGSVVTQSSP------- 683
            .    || :::|.:   |.  .|..:.:..:.::.|.|..::..|...|...:|...|
  Fly   733 QNDFGMGVYTEPVI---GI--TLPAVSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGDI 792

  Fly   684 ---TLPPSGYRSSVPPPASSPLPPPVVASSHK------------SATPAPLQR--------SLVN 725
               .|..:|.|::..|          |:...:            |.|...:|.        |:.|
  Fly   793 EYFQLAFNGTRNNFAP----------VSFERRVELDTGNKQGRMSYTETEMQPQFDYTVEVSVKN 847

  Fly   726 GSIEPIYENVPLPQRASGGSSGAANTEAMRQRASSIQSAPGVVPVPAARNASSNNVVTVTVNSPP 790
            ..:|.:..:||...::..|.....:.|.::|..::::.             :||...|..|..|.
  Fly   848 RDVEQLSSSVPGSWQSPAGLPTIPSDELIKQMRANVEE-------------TSNPTKTAIVRLPA 899

  Fly   791 D-----DGNIK-----------------KY---------------GADRAASTELLF------LE 812
            |     .|:||                 ||               |||......|.:      ..
  Fly   900 DIMTSASGDIKWMALMISQKNCAGVPHLKYDVSSDWPKVLSYQEAGADGTGDCSLEYQTTEERWH 964

  Fly   813 PQAPKRTNRAASAAPDMGATPPPRQHRSTASLNKSSTVDM------ITPAGD--TLQQQFSAMNL 869
            |:..:|..|......|       .:...|..|:|.|.|..      :.|..|  .:.:.|:|...
  Fly   965 PEPVQRQRRDGEVTSD-------EEIVFTIGLDKCSEVQKTYCNGPLLPDTDYNVVVRLFTASGY 1022

  Fly   870 S--ANTSASTSSMFNSTLDTTSSSAASKDLKRKKRWNFLSRSKTPDKQKSATLGREKATTAGQHS 932
            |  |..:..|.:....||...|..:.                    ...:..||   .|......
  Fly  1023 SDAAVLNFKTKAAIKVTLILVSVCSC--------------------LLLAFVLG---LTVLWVRK 1064

  Fly   933 KLAAKLKLAQDDLNLPNRWSTGVNKPQPISGRYSKDKLCQILDQKLSDSQLFMEFERIPKRREHA 997
            :||.|....|           |:..|   .|............:.....:|..||:.|.......
  Fly  1065 RLAWKRDSGQ-----------GIEDP---FGNVIAKNFAIFYTEVAKPEKLAREFKEITVVALEL 1115

  Fly   998 LYECALLEENEPKNHDPNFLPYDDNRVRLTPCRDNRHGYVNASSISATVGTKQRFYIVAQSPQEP 1062
            .|..:  |....||...:..|||.|||.|....:. ..|:|||.|..  .|:::.||..|.| :|
  Fly  1116 SYSAS--ELGCHKNRYADIFPYDKNRVILDIDAEG-SDYINASFIDG--HTRKKEYIATQGP-KP 1174

  Fly  1063 LTMRIFWQCVWEADVYLVVQLTEDMSYIPRNSHQRLEFGQFQV--------YQEFSQTTDRCTTI 1119
            .::..||:.:.:.:|.::||:|:   :...|:.:..|:..:.|        .:|..:..||   .
  Fly  1175 ESVMDFWRMILQYNVRVIVQVTQ---FREGNTIKCHEYYPYNVRGLTVTIKSKEVLELYDR---T 1233

  Fly  1120 KLRLYHVPSRRYRSVWYLQYADWAEQNCPRDVNHFLDFLEELNSVRLASTQEVPPGHNTNPPVLL 1184
            :|.:.|........|.:..:..|.:...|.|..|.:.|::::.:       |..|.::   |:::
  Fly  1234 ELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMFVKKVKA-------EKRPSYS---PIVV 1288

  Fly  1185 HCLEGGGRSGVTLTADLLLYTLDHNEDLDIPRVIGQLRHQRDSIIPSLAQYKFIY 1239
            ||..|.||:|..:..||::..|.....::|...:.:||.||..::.:..||.|:|
  Fly  1289 HCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQQYTFLY 1343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pez	NP_609013.1	FERM_F1_PTPN14_like	17..107	CDD:340619
		FERM_M	112..230	CDD:459788	2/2 (100%)
		FERM_C_PTPN14_PTPN21	225..317	CDD:270009	20/89 (22%)
		PTP_DSP_cys	1036..1246	CDD:475123	52/212 (25%)
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	23/133 (17%)
		PTPc	1100..1345	CDD:214550	67/266 (25%)