Protein Alignment Pez and ZK354.8

DIOPT Version :10

• Sequence 1: NP_609013.1
• Gene: Pez / 33882
• FlyBaseID: FBgn0031799
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_500775.1
• Gene: ZK354.8 / 191295
• WormBaseID: WBGene00022709
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 104/553 - (18%)
• Similarity: 193/553 - (34%)
• Gaps: 144/553 - (26%)

  Fly   736 PLPQRASGGSSGAANTEAMRQRASSIQSAPGVVPVPAARNASSNNVVTVTVNSPPDDGNIKKYGA 800
            |.|::::|.          :::.|.:...|           |..:||:|...|..:...::....
 Worm     3 PKPKKSTGA----------KKKVSKLNKRP-----------SKISVVSVNERSKNERSVMQSIEQ 46

  Fly   801 DRAASTELLFLEPQAPKRTNRAASAAP--------------------------DMGATPPP-RQH 838
            :.|.:.|::    ..||:|....:..|                          |....||| ..|
 Worm    47 EEATNNEIV----PTPKKTTAQIAQQPTPTLPQIIAKQEPEVAMKTMMLPPPSDPPPPPPPVAPH 107

  Fly   839 RSTASLNKSSTVDMITPAGDTLQQQFSAMNLSANTSASTSSMFNSTLDTTSSSAASKDLKRKKRW 903
            :....|..|:.    .|....:..|...|   :...|...||....|.:.|..|   |:..::.
 Worm   108 QPPPQLATSAQ----PPQPPVINSQLPRM---SPAPAIPPSMAQPLLQSPSPGA---DIAIRRP- 161

  Fly   904 NFLSRSKTPDKQKSATLGREKATTAGQHSKLAA---KLKLAQDDLNLPNRWSTGVNK-PQPISGR 964
               |:.||.:|....|.|.:|.    :.:::..   :|.|......|...:....|: |:.|:
 Worm   162 ---SKEKTDEKSVDETGGSDKK----KRTEVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIA-- 217

  Fly   965 YSKDKLCQILDQKLSDSQLFMEFERIPKRREHALYECALLEENEPKNHDPNFLPYDDNRVRLTPC 1029
                                ..|...|.|..:....|.                 |..||:||
 Worm   218 --------------------TSFLGNPTRNRYRNIPCC-----------------DITRVKLT-- 243

  Fly  1030 RDNRHGYVNASSISATVGTKQRFYIVAQSPQEPLTMRIFWQCVWEADVYLVVQLTE--------D 1086
             |:.|.|::|:.:|:  |...|.:|..|:|... |:..||:.:....:..:|.|.|        .
 Worm   244 -DDPHFYIHANLVSS--GPNPRRFICTQAPLNG-TIEEFWKMIIVTGIEYIVMLCELVEKGKPKS 304

  Fly  1087 MSYIPRNSHQRLEFGQF-QVYQEFSQTTDRCTTIKLRLYHVPSRR--YRSVWYLQYADWAEQNCP 1148
            ..|.|....|..:.|:. .|.:|.....|:...:.......|...  .:.|.::.:.:|.:...|
 Worm   305 AEYFPSQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVP 369

  Fly  1149 RDVNHFLDFLEELNSVRLASTQEVPPGHNTNPPVLLHCLEGGGRSGVTLTADLLLYTLDHNEDLD 1213
               ::||.....|..|:           |...|:::||..|.||:|......::|.::...:.:.
 Worm   370 ---DNFLSPFRLLTVVK-----------NCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIG 420

  Fly  1214 IPRVIGQLRHQRDSIIPSLAQYKFIYNLLITYL 1246
            :||::.:||.:|...:.:..||.:.:..::.||
 Worm   421 VPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pez	NP_609013.1	FERM_F1_PTPN14_like	17..107	CDD:340619
		FERM_M	112..230	CDD:459788
		FERM_C_PTPN14_PTPN21	225..317	CDD:270009
		PTP_DSP_cys	1036..1246	CDD:475123	45/220 (20%)
ZK354.8	NP_500775.1	PTPc	200..451	CDD:214550	60/309 (19%)