DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pez and sdf-9

DIOPT Version :9

Sequence 1:	NP_001260127.1	Gene:	Pez / 33882	FlyBaseID:	FBgn0031799	Length:	1252	Species:	Drosophila melanogaster
Sequence 2:	NP_508013.2	Gene:	sdf-9 / 189901	WormBaseID:	WBGene00004748	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	312	Identity:	78/312 - (25%)
Similarity:	113/312 - (36%)	Gaps:	77/312 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   977 KLSDSQLFMEFERIPKRREHALYECALLEENEPKNHDPNFLPYDDNRVRLTPCRDNRHGYVNASS 1041
            ||.|:|..:. ||:..|.|..           .:|.....:|.....|||||...||.||:|||.
Worm    13 KLDDNQPLLS-ERVTARLEAV-----------NRNRVVKIVPQHRYNVRLTPSMLNRDGYINASL 65

  Fly  1042 IS-ATVGTKQRFYIVAQSPQEPLTMRIFWQCVWEADVYLVVQLTEDM--------SYIPRN---- 1093
            :. :.||.|   ||:...|.|.... .|||.|.|.....::|..:::        .|.|..
Worm    66 MEFSDVGQK---YILTGIPSEDKVF-AFWQMVLEQRSPTIIQFADNVEEKLEHYDKYFPDKGDVW 126

  Fly  1094 --SHQRLEFGQFQVYQEFSQTTDRCTTIKLRLYHVPSRRYRSVWYLQYADWAEQNCPRDVNHFLD 1156
              .|.::|...:.::|....|.:    ..||..:...|    |.:.....|.|...|    ...|
Worm   127 SYGHLQVERKSYAIHQGNFHTRN----FILRKGNETHR----VLHFTVFGWTETTTP----IMQD 179

  Fly  1157 FLE---------ELNSVRLASTQ---------EVPPGHNTNPPVLLHCLEGGGRSGVTLTADLLL 1203
            ||.         .||.:..||..         ..||..   .|: :....|..|:|..:..|||:
Worm   180 FLALRKVMKDTGALNMINPASALFRSTMRRYIHTPPSF---API-IQSARGSSRAGAFVVIDLLI 240

  Fly  1204 YTLDHN-------EDLDIPRVIGQLRHQRDSIIPSLAQYKFIYNLLITYLKR 1248
            ..:|..       |||     |.:.:|.|...:|....:.|||..::.||.|
Worm   241 RMIDGKKTNLYSVEDL-----IVKCKHMRIHCVPVALHHSFIYEAVLDYLLR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pez	NP_001260127.1	B41	26..230	CDD:214604
		FERM_N	26..93	CDD:286467
		FERM_M	114..230	CDD:278785
		FERM_C_PTPN14_PTPN21	225..317	CDD:270009
		Y_phosphatase	1007..1243	CDD:278528	67/275 (24%)
		PTPc	1009..1243	CDD:238006	67/273 (25%)
sdf-9	NP_508013.2	PTPc	7..283	CDD:214550	75/306 (25%)
sdf-9	NP_508013.2	PTPc	34..283	CDD:304379	67/273 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D144506at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920