Protein Alignment Pez and C46A5.1

DIOPT Version :10

• Sequence 1: NP_609013.1
• Gene: Pez / 33882
• FlyBaseID: FBgn0031799
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: NP_501277.1
• Gene: C46A5.1 / 183497
• WormBaseID: WBGene00016698
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 117/584 - (20%)
• Similarity: 205/584 - (35%)
• Gaps: 164/584 - (28%)

  Fly   712 KSATPAPLQRSLVNGSIEPIYENVPLPQRASGGSSGAANTEAMRQRASSIQSAP--GVVPVPAAR 774
            |:...||.::|         :|.....:|...| :|.|.....|:..|..::.|  |:......:
 Worm     2 KAVDQAPKKKS---------HERKRKEKRVHTG-NGTAKKHHKRKSRSKSKNKPKNGLSCCRKKK 56

  Fly   775 NASSNNVVTVTVNSP-----------PDD--GNIKKYGADRAASTELLFLEPQAPKRTNRAASAA 826
            ..|..:...||...|           |::  |.:            :|....:.|:...:..:..
 Worm    57 KKSKKSKSKVTKKQPKKKVIKPLAPVPNEQLGEV------------VLVKNVKLPETPQKPENDT 109

  Fly   827 PDMGATPPPRQHRSTASLNKSSTVDMITPAGDTLQQQFSAMNLS----ANTSASTSSMFNSTLDT 887
            |......|||...|...:|.|.                .:.|||    |:.:.:...|....:|
 Worm   110 PVKDGLKPPRTTNSVEKINLSK----------------ESFNLSNEKIASDNGTEEKMEKKNVD- 157

  Fly   888 TSSSAASKD-LKRKKRWNFLSRSKTPDKQKSATLGREKATTAGQHSKLAAKLKLAQDDLNLPNRW 951
              |.|..:| ||.|            .||||.....:||....:......|.|::.:.|   .:|
 Worm   158 --SPADIQDGLKGK------------SKQKSEEKVHQKAKDDAKRGDECNKFKISDEKL---TKW 205

  Fly   952 STGVNKPQPISGRYSKDKLCQILDQKLSDSQ--LFMEFERI----PKR--REHALYECALLEENE 1008
                             ||  :..:.|.|..  ...|||::    |..  :.|.:       .|.
 Worm   206 -----------------KL--VAQETLKDDANIAVNEFEKVSGYLPPHISKNHFV-------SNM 244

  Fly  1009 PKNHDPNFLPYDDNRVRLTPCRDNRHGYVNASSISATVGTKQRFYIVAQSPQEPLTMRIFWQCVW 1073
            .||...:.:..|.:||:||.     ..|::|:.:......|.   |:.|.|... |...|||.:.
 Worm   245 DKNRFVDVICMDHSRVKLTD-----SSYIHANWVDLNSSKKA---ILTQLPLSH-TASDFWQMII 300

  Fly  1074 EADVYLVVQLTEDMSYIPRNSHQRLEFGQFQVY---QEFSQTTDRCTTI------------KLRL 1123
            :..:..|:.:..|..:        .:||...|:   |:|.:..||...:            .|::
 Worm   301 DQKIKCVLLIMTDGEF--------NKFGGNSVFPQNQDFLKFEDRFIRVGEFKQVELGKGWNLKV 357

  Fly  1124 YHVPSRRYRSVWYL-QYADWAEQNCPRDVNHFLDFLEELNSVRLASTQEVPPGHNTNPPVLLHCL 1187
            ..|.:..|::..:: .|.:|...:.|.||.........|        ::...||   |||.: .:
 Worm   358 LSVSNGTYKTFIHVHHYKNWPHGSIPSDVKQIWQVQSYL--------RKYTDGH---PPVYM-SM 410

  Fly  1188 EGGGRSGVTL---TADLLLYTLDHNE--DLDIPRVIGQLRHQRDSIIPSLAQYKFIYNLLITYL 1246
            .|.||:|...   ||.:.|    |||  .|::.:.:..:|:.|...:.:|:|:..:|.|:..::
 Worm   411 SGCGRAGTFALFETAHMSL----HNEQPSLNMVKCLENVRNGRLHSVQNLSQFSVVYTLIAEHV 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pez	NP_609013.1	FERM_F1_PTPN14_like	17..107	CDD:340619
		FERM_M	112..230	CDD:459788
		FERM_C_PTPN14_PTPN21	225..317	CDD:270009
		PTP_DSP_cys	1036..1246	CDD:475123	50/230 (22%)
C46A5.1	NP_501277.1	Y_phosphatase	243..468	CDD:459674	58/257 (23%)