| Sequence 1: | NP_001260127.1 | Gene: | Pez / 33882 | FlyBaseID: | FBgn0031799 | Length: | 1252 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_598229.2 | Gene: | Ptpn21 / 171070 | RGDID: | 620216 | Length: | 1175 | Species: | Rattus norvegicus |
| Alignment Length: | 1362 | Identity: | 378/1362 - (27%) |
|---|---|---|---|
| Similarity: | 605/1362 - (44%) | Gaps: | 297/1362 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MPLKF---LKKCRQYNVTSKSLFVISVHHLLDTSSTVDCTISSESKGQECLDNVCQRLLIQQPEF 62
Fly 63 FGLRYLVKGKDKEDEFKWIDLERSLSRQLEKYAAGPKIYLRVRHYVTTGVRHLSDEATRFYYFLQ 127
Fly 128 LKSDIYEGRIACDIRTAILLALYCRQA---EYDSYQGDKQSKDYLKKSLVLPRNMQGLANDDSML 189
Fly 190 EGLIVEVLQQQAGIAH-----LSQSQAEEMYIQCCQQLEGYGEERFAAKDTLGNDLLLGLAINGM 249
Fly 250 VVNADNGRQ--YFPWKEFHTVTIDKRTIKIE-QNKLDGGGSIVGSFIFSEADTARYFWKLTISQH 311
Fly 312 KFFK-----RYIDTATPSSLGSGADAESG-----PLGVDSVGYVDYD--YNEAAAAEQLQQHHQQ 364
Fly 365 QQHMQQQQQIQQQQMISSNISLATSANQMLGQSSSCLDLSNNNLHSSSGMLHHGG-----SNNNN 424
Fly 425 NNDE--------------------------RERLKAML-PTYRPAPDYETAV-QLKYRTPSAEFH 461
Fly 462 NVALAMAAPGNAYYAGSQPDVHNPGMHNENLLYGHMTAHRYPDVAQPAAALHHHINLYQAQHQPQ 526
Fly 527 SHPQPMS----------PAQAYLELSQR-------MHMMRHKAPPPYVNRLSSSSTPDLAVATPR 574
Fly 575 PLQGFRNYVSGSSPDLVSNRTLFNGGQYVALPAGGHAGNIPTSSGATMLHQYQYVSHMGHSQPYL 639
Fly 640 PP-HGTFENLNMIEEQPSIMS--------QLRQSAMSQAAAAAAGSVVTQSSPTLPPSGYRSSVP 695
Fly 696 PPASSPLPPPVVASSHKSATPAPLQRSLVNGSIEPIYENVPLPQRASGGSSGAANTEAMRQRASS 760
Fly 761 IQSAPGVVPVPAARNASSNNVVTVTVNSPPDDGNIKKYGADRAASTE--LLFLEPQAPKRTNRAA 823
Fly 824 SAAPDMGATPP-----PRQHRSTASLNKSSTVDMITPAGDTLQQQFSAMNLSANTSASTSSMFNS 883
Fly 884 TLDTTSSSAASKDLKRKKRWNFLSRSKTPDKQKSATLGREKATTAGQHS----KLAAKLKLAQDD 944
Fly 945 LNLPNRWSTGVNKPQPISGRYSKDKLCQILDQKLSDSQLFMEFERIPKRREHALY--EC--ALLE 1005
Fly 1006 ENEPKNHDPNFLPYDDNRVRLTPCRDNRHGYVNASSISATVGTKQRFYIVAQSPQEPLTMRIFWQ 1070
Fly 1071 CVWEADVYLVVQLT--------EDMSYIPR--NSHQRLEFGQFQVYQEFSQTTDRCTTIKLRLYH 1125
Fly 1126 VPSRRYRSVWYLQYADWAEQNCPRDVNHFLDFLEELNSVRLASTQEVPPGHNTNPPVLLHCLEGG 1190
Fly 1191 GRSGVTLTADLLLYTLDHNEDLDIPRVIGQLRHQRDSIIPSLAQYKFIYNLLITYLKRTRLI 1252 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pez | NP_001260127.1 | B41 | 26..230 | CDD:214604 | 78/211 (37%) |
| FERM_N | 26..93 | CDD:286467 | 25/66 (38%) | ||
| FERM_M | 114..230 | CDD:278785 | 45/123 (37%) | ||
| FERM_C_PTPN14_PTPN21 | 225..317 | CDD:270009 | 30/99 (30%) | ||
| Y_phosphatase | 1007..1243 | CDD:278528 | 93/245 (38%) | ||
| PTPc | 1009..1243 | CDD:238006 | 92/243 (38%) | ||
| Ptpn21 | NP_598229.2 | FERM_F1_PTPN21 | 20..106 | CDD:340712 | 34/91 (37%) |
| B41 | 24..222 | CDD:214604 | 79/216 (37%) | ||
| FERM_C_PTPN14_PTPN21 | 217..307 | CDD:270009 | 30/94 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 395..445 | 6/49 (12%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 663..702 | 9/107 (8%) | |||
| PTP_DSP_cys | 884..1170 | CDD:421693 | 112/290 (39%) | ||
| Substrate binding. /evidence=ECO:0000250 | 1109..1115 | 2/5 (40%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 184 | 1.000 | Domainoid score | I3324 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 450 | 1.000 | Inparanoid score | I1562 |
| OMA | 1 | 1.010 | - | - | QHG47166 | |
| OrthoDB | 1 | 1.010 | - | - | D144506at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0004427 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46341 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105256 | |
| Panther | 1 | 1.100 | - | - | O | PTHR45706 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X3138 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 11.070 | |||||