| Sequence 1: | NP_609012.2 | Gene: | PDZ-GEF / 33881 | FlyBaseID: | FBgn0265778 | Length: | 1573 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_076111.2 | Gene: | Rgl3 / 71746 | MGIID: | 1918996 | Length: | 709 | Species: | Mus musculus |
| Alignment Length: | 509 | Identity: | 109/509 - (21%) |
|---|---|---|---|
| Similarity: | 185/509 - (36%) | Gaps: | 120/509 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 851 ELALELVRE-----SNVHFLHLNAYELAIQLTLQDFANFRQIESTEYVDELFELRSRYGV----P 906
Fly 907 MLSKFAELVNREMFWVVSEICAEHNIV--RRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGHGA 969
Fly 970 VSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAE------------LLAQHP--IIP 1020
Fly 1021 FYPIVKKDLTFIHLG-NDTRVDGLINFEKLR----MLAKEVRLLTHMCSSPYDLLSILELKGQSP 1080
Fly 1081 S----NALFSLNQMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVKAYL 1141
Fly 1142 NSLKILSDEDLLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGSSGGGGGGSSSLN 1206
Fly 1207 AGDQLSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRRQMHNNGPKFGTASPQAV 1271
Fly 1272 KKMLSLSESSKIRPHQPFV-PRHGSTMAGVI------PPLHHMHAAHGFSTPSP 1318 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PDZ-GEF | NP_609012.2 | CAP_ED | 128..237 | CDD:237999 | |
| RasGEFN | 279..400 | CDD:214571 | |||
| PDZ_signaling | 404..494 | CDD:238492 | |||
| DegQ | <422..494 | CDD:223343 | |||
| PDZ_GEF_RA | 757..841 | CDD:176380 | |||
| RasGEF | 871..1050 | CDD:279011 | 52/199 (26%) | ||
| Rhomboid_SP | 1252..>1357 | CDD:289371 | 14/74 (19%) | ||
| Rgl3 | NP_076111.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..55 | ||
| REM | 73..199 | CDD:100121 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 203..225 | ||||
| RasGEF | 244..503 | CDD:214539 | 68/281 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 395..416 | 3/20 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 502..604 | 28/157 (18%) | |||
| Interaction with HRAS, MRAS and RIT1. /evidence=ECO:0000269|PubMed:10869344, ECO:0000269|PubMed:11313946 | 611..706 | 8/45 (18%) | |||
| RalGDS_RA | 612..697 | CDD:176351 | 7/44 (16%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3629 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||