DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PDZ-GEF and 4933421I07Rik

DIOPT Version :9

Sequence 1:	NP_609012.2	Gene:	PDZ-GEF / 33881	FlyBaseID:	FBgn0265778	Length:	1573	Species:	Drosophila melanogaster
Sequence 2:	NP_001357701.1	Gene:	4933421I07Rik / 71162	MGIID:	1918412	Length:	316	Species:	Mus musculus

Alignment Length:	112	Identity:	25/112 - (22%)
Similarity:	43/112 - (38%)	Gaps:	29/112 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 YSGSDTMASNYASSLEAEEIDLSGLVE---SVVDSDEEDLAESMDSLTVRDAVRDCLEKDPAERS 112
            :...||.|....|..:.:|.....|.|   :..|..|:|::...|:|.:|          ||..:
Mouse   167 FGDGDTQAREPLSMFKDQEAITLRLEEDCATTPDPPEQDVSGRQDTLALR----------PASMA 221

  Fly   113 EEDVEVLLEFTQGLKAFTNITLAVRRAL-------CSVMVFAVVDKA 152
            |         .||.|.....|:.|:||:       .::.:...:|:|
Mouse   222 E---------PQGDKQSREDTVLVKRAVLDPFEPKAAIELLPTLDQA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PDZ-GEF	NP_609012.2	CAP_ED	128..237	CDD:237999	6/32 (19%)
		RasGEFN	279..400	CDD:214571
		PDZ_signaling	404..494	CDD:238492
		DegQ	<422..494	CDD:223343
		PDZ_GEF_RA	757..841	CDD:176380
		RasGEF	871..1050	CDD:279011
		Rhomboid_SP	1252..>1357	CDD:289371
4933421I07Rik	NP_001357701.1	REM	89..166	CDD:321967
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900