DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PDZ-GEF and Gm6370

DIOPT Version :9

Sequence 1:	NP_609012.2	Gene:	PDZ-GEF / 33881	FlyBaseID:	FBgn0265778	Length:	1573	Species:	Drosophila melanogaster
Sequence 2:	NP_001361660.1	Gene:	Gm6370 / 622924	MGIID:	3779587	Length:	315	Species:	Mus musculus

Alignment Length:	138	Identity:	34/138 - (24%)
Similarity:	47/138 - (34%)	Gaps:	18/138 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1242 TSSTSSTSDHQRRQMHNNGPKFGTASPQAVKKMLSLSESSKIRPHQPFVPRHGSTMAGVIPPLHH 1306
            |:...|..|...||............||..|:....:|..|.....||.|:  :|:.  :.|..|
Mouse   196 TAPEPSEQDASGRQETLAPRPASETEPQGDKQHREDAELVKGAVLDPFKPK--ATIE--LHPTLH 256

  Fly  1307 MHAAHGFSTPSPGGVVTSPATSAVANVQCTPSPSPCSHRRLASGGNIIPSRAIHERSHSDTPAPP 1371
            ........:.||..|....||...|:|....||:    |:|.....:          ...||...
Mouse   257 QAVPTSDGSLSPVDVTADEATGVAADVAADVSPA----RQLFVSYTV----------QLGTPDFI 307

  Fly  1372 PPLPSVDL 1379
            .|||.||:
Mouse   308 FPLPEVDI 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PDZ-GEF	NP_609012.2	CAP_ED	128..237	CDD:237999
		RasGEFN	279..400	CDD:214571
		PDZ_signaling	404..494	CDD:238492
		DegQ	<422..494	CDD:223343
		PDZ_GEF_RA	757..841	CDD:176380
		RasGEF	871..1050	CDD:279011
		Rhomboid_SP	1252..>1357	CDD:289371	24/104 (23%)
Gm6370	NP_001361660.1	REM	89..177	CDD:100121
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900