Sequence 1: | NP_609012.2 | Gene: | PDZ-GEF / 33881 | FlyBaseID: | FBgn0265778 | Length: | 1573 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001155088.2 | Gene: | RGL3 / 57139 | HGNCID: | 30282 | Length: | 716 | Species: | Homo sapiens |
Alignment Length: | 607 | Identity: | 117/607 - (19%) |
---|---|---|---|
Similarity: | 194/607 - (31%) | Gaps: | 226/607 - (37%) |
- Green bases have known domain annotations that are detailed below.
Fly 842 DSTEPLVPDELALELVRESNVHFLHLNAYELAIQLTLQDFANFRQIESTEYVDELFELRSRYGV- 905
Fly 906 ---PMLSKFAELVNREMFWVVSEICAEHNIV--RRMKIVKQFIKIARHCKECRNFNSMFAIVSGL 965
Fly 966 GHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPI------------ 1018
Fly 1019 ----------IPFYPIVKKDLTFIHLGNDTRVDG-LINFEKLR----MLAKEVRLLTHMCSSPYD 1068
Fly 1069 LLSILELKGQSPS----NALFSLNQMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFE 1129
Fly 1130 EAQMVRRVKAYLNSLKILSDEDLLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGS 1194
Fly 1195 SGGGGGGSSSLNAGDQLSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRRQMHNN 1259
Fly 1260 GPKFGTASPQAVKKMLSLSESSKIRPHQPFVPRHGSTMAGVIPPLHHMHAAHGFSTPSPGGVVTS 1324
Fly 1325 PATSAVANVQCTPSPSPCSHRRLASGGNIIPSRAIHERSHSDTPAPPPPLPS--------VDLSL 1381
Fly 1382 ESSSVTTFRDLPLRKSVTSGSI 1403 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
PDZ-GEF | NP_609012.2 | CAP_ED | 128..237 | CDD:237999 | |
RasGEFN | 279..400 | CDD:214571 | |||
PDZ_signaling | 404..494 | CDD:238492 | |||
DegQ | <422..494 | CDD:223343 | |||
PDZ_GEF_RA | 757..841 | CDD:176380 | |||
RasGEF | 871..1050 | CDD:279011 | 50/207 (24%) | ||
Rhomboid_SP | 1252..>1357 | CDD:289371 | 17/104 (16%) | ||
RGL3 | NP_001155088.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 28..54 | ||
REM | 74..196 | CDD:100121 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 198..234 | 4/12 (33%) | |||
RasGEF | 243..505 | CDD:214539 | 67/289 (23%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 397..419 | 0/21 (0%) | |||
Interaction with HRAS, MRAS and RIT1. /evidence=ECO:0000250 | 618..713 | 4/32 (13%) | |||
RalGDS_RA | 619..704 | CDD:176351 | 4/31 (13%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3629 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |