| Sequence 1: | NP_609012.2 | Gene: | PDZ-GEF / 33881 | FlyBaseID: | FBgn0265778 | Length: | 1573 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_009291904.1 | Gene: | rasgrf1 / 568885 | ZFINID: | ZDB-GENE-090311-28 | Length: | 1263 | Species: | Danio rerio |
| Alignment Length: | 973 | Identity: | 180/973 - (18%) |
|---|---|---|---|
| Similarity: | 351/973 - (36%) | Gaps: | 264/973 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 289 ERLLQQLVEENSMTDPTYVEDFLLTHRIFIQNPQE---------VTSKLLHWFDLEQVDAHKTQE 344
Fly 345 LRDRVTRVVLLWVNNHFTDFEADYEMMEFLEVFEALLE------RKKLLSQLRLLHIACAAKARM 403
Fly 404 RSCTLTRSSRDEPLNFRIVGGYELRGVAIATGNAAVGIYISHVEPGSKAQDV------------- 455
Fly 456 GLKRGDQIHEVNGQSLDHVTSKRALE---------ILTGTTHLSIS------------VKSNLLG 499
Fly 500 FKEIMQALEHGGGTAGSGSISAGSG--------SFKSVRSPRRICANDIAKLHGRSDSTTD-ELS 555
Fly 556 SVSASNR-AHMVRL-SSVDMLLD-------QPDCA----------------------PPQT---- 585
Fly 586 ------PPVSGSGNMASNFMQQLLQSVN----------NSSAKKSGGNSNSDQQDTKGGF--MTL 632
Fly 633 --------AP---------KRRLQKALAKMNLLNKQNHGSSLNDSSDTLLNDPKSKLSAVSS--- 677
Fly 678 -----CSSSTQSSI----NGCTVSGGGRLYQSQSNPDLTSLNYDGGSDAGGNGGGRLQVNYLNAH 733
Fly 734 IHRPSAASTLTTNSTQSHLLPDYP-----------------DHVLKVYKADQTCKYVLIYKETTA 781
Fly 782 HEVVMLTLQEFGIHDPSSNFSLCEVSVGDGGMVKQRRLPDQLQNLAERISFAARYYLKLNDSTEP 846
Fly 847 LVPDELALELVRE-----SNVHFLHLNAYELAIQLTLQDFANFRQIESTEYVDELFELRSR-YGV 905
Fly 906 PMLSKFAELVNREMFWVVSEI--CAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGHG 968
Fly 969 AVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYPIVKKDLTFIH 1033
Fly 1034 LG--NDTRVDGLINFEKLRMLAKEVRLLTHMCSSPYDLLSILELKGQSPSNALFSLNQMSASQ 1094 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PDZ-GEF | NP_609012.2 | CAP_ED | 128..237 | CDD:237999 | |
| RasGEFN | 279..400 | CDD:214571 | 23/125 (18%) | ||
| PDZ_signaling | 404..494 | CDD:238492 | 18/123 (15%) | ||
| DegQ | <422..494 | CDD:223343 | 15/105 (14%) | ||
| PDZ_GEF_RA | 757..841 | CDD:176380 | 14/100 (14%) | ||
| RasGEF | 871..1050 | CDD:279011 | 49/183 (27%) | ||
| Rhomboid_SP | 1252..>1357 | CDD:289371 | |||
| rasgrf1 | XP_009291904.1 | PH_RasGRF1_2 | 19..154 | CDD:270081 | |
| PH | 24..129 | CDD:278594 | |||
| RhoGEF | 244..425 | CDD:214619 | 12/56 (21%) | ||
| PH-like | 474..596 | CDD:302622 | 19/129 (15%) | ||
| PH | 489..592 | CDD:278594 | 16/110 (15%) | ||
| RasGEF_N | 643..>691 | CDD:279012 | 11/47 (23%) | ||
| REM | <928..997 | CDD:295342 | 13/96 (14%) | ||
| RasGEF | 1024..1261 | CDD:214539 | 59/236 (25%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2063 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||