| Sequence 1: | NP_609012.2 | Gene: | PDZ-GEF / 33881 | FlyBaseID: | FBgn0265778 | Length: | 1573 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001101154.1 | Gene: | Rapgef2 / 310533 | RGDID: | 1306434 | Length: | 1294 | Species: | Rattus norvegicus |
| Alignment Length: | 1497 | Identity: | 524/1497 - (35%) |
|---|---|---|---|
| Similarity: | 717/1497 - (47%) | Gaps: | 406/1497 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 188 MGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQGEENTRRHEDENGFVVMVTELR 252
Fly 253 SIGGAGTDSAGSGGSATGASASLNMKRGHVVIRGTPERLLQQLVEENSMTDPTYVEDFLLTHRIF 317
Fly 318 IQNPQEVTSKLLHWFDLEQVDAHKTQELRDRVTRVVLLWVNNHFTDFEADYEMMEFLEVFEALLE 382
Fly 383 RKKLLSQLRLLHIACAAKARMRSCTLTRSSRDEPLNFRIVGGYELRGVAIATGNAAVGIYISHVE 447
Fly 448 PGSKAQDVGLKRGDQIHEVNGQSLDHVTSKRALEILTGTTHLSISVKSNLLGFKEIMQALEHGGG 512
Fly 513 TAGSGSISAGSGSFKSVRSPRRICANDIAKLHGRSDSTTDELSSVSASNRAHMVRLSSVDMLLDQ 577
Fly 578 PDCAPPQTPPVSGSGNMASNFMQQL--LQSVNNSSAKKSGGNSNSDQQDTKGGFMTLAPKRRLQK 640
Fly 641 ALAKMNL-------LNKQNHGSSLNDSSDTLLNDPKSKLSAVSSCSSSTQSSINGCTVSGGGRLY 698
Fly 699 QSQSNPDLTSLNYDGGSDAGGNGGGRLQVNYLNAHIHRPSAASTLTTNSTQSHLLPDYPDHVLKV 763
Fly 764 YKADQTCKYVLIYKETTAHEVVMLTLQEFGIHDPSSNFSLCEVSVGDGGMVKQRRLPDQLQNLAE 828
Fly 829 RISFAARYYLKLNDSTEPLVPDELALELVRESNVHFLHLNAYELAIQLTLQDFANFRQIESTEYV 893
Fly 894 DELFELRSRYGVPMLSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSM 958
Fly 959 FAIVSGLGHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYP 1023
Fly 1024 IVKKDLTFIHLGNDTRVDGLINFEKLRMLAKEVRLLTHMCSSPYDLLSILELKGQSPSNALFSLN 1088
Fly 1089 QMSASQSNAAAGTV--IAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVKAYLNSLKILSDED 1151
Fly 1152 LLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGSSGGGGGGSSSL--NAGDQLSIY 1214
Fly 1215 SHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQ---------RRQMH-NNGPKFGTASPQ 1269
Fly 1270 AVKKMLSLSESSKIRPHQPFVPRHGSTMAGVIPPLHHMHAAHGFSTPSPGGVVTSPATS-----A 1329
Fly 1330 VANVQCTPSPSPCSHRRLASGGNIIPSR-------AIHE------------------RSHSDTPA 1369
Fly 1370 PPPPLPSVDLSLES-SSVTTFRDLPLRKSVTS------------------------GSISSCDSG 1409
Fly 1410 -------YVHQQQ-------HYHLQY---------------------------QQQQQQNSSQHE 1433
Fly 1434 PSPPVYTAADCRLLQQISNNAVT------RNLNSPCQSTNTPPST-----PTPPPNQ----PTAT 1483
Fly 1484 IQLSA---------PPTAAAYM------------H-ARS--QHQQLQQQQQSLAMPPPPPPPYNV 1524
Fly 1525 PP 1526 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PDZ-GEF | NP_609012.2 | CAP_ED | 128..237 | CDD:237999 | 33/48 (69%) |
| RasGEFN | 279..400 | CDD:214571 | 71/120 (59%) | ||
| PDZ_signaling | 404..494 | CDD:238492 | 41/89 (46%) | ||
| DegQ | <422..494 | CDD:223343 | 31/71 (44%) | ||
| PDZ_GEF_RA | 757..841 | CDD:176380 | 46/83 (55%) | ||
| RasGEF | 871..1050 | CDD:279011 | 109/178 (61%) | ||
| Rhomboid_SP | 1252..>1357 | CDD:289371 | 32/119 (27%) | ||
| Rapgef2 | NP_001101154.1 | RasGEFN | 73..186 | CDD:214571 | 71/120 (59%) |
| PDZ_signaling | 190..270 | CDD:238492 | 41/89 (46%) | ||
| UBQ | 412..496 | CDD:294102 | 46/83 (55%) | ||
| RasGEF | 519..723 | CDD:238087 | 121/215 (56%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 239 | 1.000 | Domainoid score | I2205 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 881 | 1.000 | Inparanoid score | I385 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D21656at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002053 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46019 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104221 | |
| Panther | 1 | 1.100 | - | - | O | PTHR23113 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X1353 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.970 | |||||