| Sequence 1: | NP_609012.2 | Gene: | PDZ-GEF / 33881 | FlyBaseID: | FBgn0265778 | Length: | 1573 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_017452748.1 | Gene: | Rapgef6 / 303141 | RGDID: | 1307645 | Length: | 1619 | Species: | Rattus norvegicus |
| Alignment Length: | 1630 | Identity: | 569/1630 - (34%) |
|---|---|---|---|
| Similarity: | 796/1630 - (48%) | Gaps: | 364/1630 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 42 SHSSDTSSAYSGSDTMASNY-ASSLEAEEIDLSGLVESVVDSDEEDLAES----MDSLTVRDAVR 101
Fly 102 DCLEKDPAERSEEDVEVLLEFTQGLKAFTNITLAVRRALCSVMVFAVVDKAGTVVMSDGEELDSW 166
Fly 167 SVLINGAVEIEHANGSREELQMGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQG 231
Fly 232 EENTRRHEDENGFVVMVTELRSIGGAGTDSAGSGGSATGASASLNMKRGHVVIRGTPERLLQQLV 296
Fly 297 EENSMTDPTYVEDFLLTHRIFIQNPQEVTSKLLHWFDLEQVDAHKTQELRDRVTRVVLLWVNNHF 361
Fly 362 TDFEADYEMMEFLEVFEALLERKKLLSQLRLLHIACAAKARMRSCTLTRSSRDEPLNFRIVGGYE 426
Fly 427 LRGVAIATGNAAVGIYISHVEPGSKAQDVGLKRGDQIHEVNGQSLDHVTSKRALEILTGTTHLSI 491
Fly 492 SVKSNLLGFKEIMQALEHGGGTAGSGSISAGSGSFKSVRSPRRICANDIAKLHGRSDSTTD---E 553
Fly 554 LSSVSASNRAHMVRLSSVDMLLDQPDCAPPQTPPVSGSGNMASNFMQQLLQSVNNSSAKKSGGNS 618
Fly 619 NSDQQDTKGGFMTLAPKRRLQKALAKMNLLNKQNHGSSLNDSSDTLLNDPKSKLSAVSSCSSSTQ 683
Fly 684 SSINGCTVSGGGRLYQSQSNPDLTSLNYDGGSDAGGNGGGRLQVNYLNAHIHRPSAASTLTTNST 748
Fly 749 QSHLLPDYPDHVLKVYKADQTCKYVLIYKETTAHEVVMLTLQEFGIHDPSSNFSLCEVSVGDGGM 813
Fly 814 VKQRRLPDQLQNLAERISFAARYYLKLNDSTEPLVPDELALELVRESNVHFLHLNAYELAIQLTL 878
Fly 879 QDFANFRQIESTEYVDELFELRSRYGVPMLSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFI 943
Fly 944 KIARHCKECRNFNSMFAIVSGLGHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLV 1008
Fly 1009 SAELLAQHPIIPFYPIVKKDLTFIHLGNDTRVDGLINFEKLRMLAKEVRLLTHMCSSPYDLLSIL 1073
Fly 1074 ELKGQSPSNALFSLNQMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVK 1138
Fly 1139 AYLNSLKILSDEDLLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGSSGGGGGGSS 1203
Fly 1204 SLNAGDQLS------------------IYSHTSSSSAPNSSLS-----LRKRHPSSPTLSTTSST 1245
Fly 1246 SSTSDHQRRQMHNNGPKFGTASPQ-AVKKMLSLSESSKI-----RPHQPFVPRHGSTMAGVIPPL 1304
Fly 1305 -----HHMHAAHGFSTPSPGGVVTSPATSAVANVQCTPSPSPCS-HRRLASGGNIIPSRAIHERS 1363
Fly 1364 HSDTPAPPPPLPSVDLSLESSSVTTFRDLPLRKSVTS--GSISSCDSGYVHQQQHYHLQYQQQQQ 1426
Fly 1427 Q----NSSQH--------EPSPPVYTAADC----------RLLQQISNNAVTRNLNSPCQST--- 1466
Fly 1467 -----------------NTPPSTP-------TPPPNQPTATIQL-------------------SA 1488
Fly 1489 PPTAAAYMH------ARSQHQQLQQQQQSLA--------------MPPPPPPPYN---VP-PLGS 1529
Fly 1530 IYSHH 1534 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PDZ-GEF | NP_609012.2 | CAP_ED | 128..237 | CDD:237999 | 67/108 (62%) |
| RasGEFN | 279..400 | CDD:214571 | 69/120 (58%) | ||
| PDZ_signaling | 404..494 | CDD:238492 | 40/89 (45%) | ||
| DegQ | <422..494 | CDD:223343 | 33/71 (46%) | ||
| PDZ_GEF_RA | 757..841 | CDD:176380 | 47/83 (57%) | ||
| RasGEF | 871..1050 | CDD:279011 | 108/178 (61%) | ||
| Rhomboid_SP | 1252..>1357 | CDD:289371 | 27/116 (23%) | ||
| Rapgef6 | XP_017452748.1 | None | |||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 239 | 1.000 | Domainoid score | I2205 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3629 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 881 | 1.000 | Inparanoid score | I385 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D21656at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002053 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46019 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104221 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23113 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X1353 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 11 | 10.960 | |||||