DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PDZ-GEF and LOC102552619

DIOPT Version :9

Sequence 1:NP_609012.2 Gene:PDZ-GEF / 33881 FlyBaseID:FBgn0265778 Length:1573 Species:Drosophila melanogaster
Sequence 2:XP_017453122.1 Gene:LOC102552619 / 102552619 RGDID:7567332 Length:206 Species:Rattus norvegicus


Alignment Length:119 Identity:26/119 - (21%)
Similarity:45/119 - (37%) Gaps:44/119 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   287 TPERLLQQLVEENSMTDPTYVEDFLLTHRIFIQNPQEVTSKLLHWFDLEQVDAHKTQELRDRVTR 351
            ||.::|..|...:|...|...||            ::|.:.|  |..||                
  Rat    98 TPLQILDLLFVRHSYLSPYSKED------------EQVKNTL--WSFLE---------------- 132

  Fly   352 VVLLWVN-NHFTDF--EADYEMMEFLEVF--------EALLERKKLLSQLRLLH 394
               .|:: |.:.||  .:|...:::||.:        :.::..|.||:||:..|
  Rat   133 ---TWMDKNPWMDFCDPSDMLPLQYLEAYLSVYIPNSDLIVRVKILLTQLQEKH 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PDZ-GEFNP_609012.2 CAP_ED 128..237 CDD:237999
RasGEFN 279..400 CDD:214571 26/119 (22%)
PDZ_signaling 404..494 CDD:238492
DegQ <422..494 CDD:223343
PDZ_GEF_RA 757..841 CDD:176380
RasGEF 871..1050 CDD:279011
Rhomboid_SP 1252..>1357 CDD:289371
LOC102552619XP_017453122.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3629
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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