Protein Alignment PDZ-GEF and zbtb22

DIOPT Version :9

• Sequence 1: NP_609012.2
• Gene: PDZ-GEF / 33881
• FlyBaseID: FBgn0265778
• Length: 1573
• Species: Drosophila melanogaster
• Sequence 2: XP_002938727.2
• Gene: zbtb22 / 100488727
• XenbaseID: XB-GENE-6458515
• Length: 436
• Species: Xenopus tropicalis
• Alignment Length: 198
• Identity: 42/198 - (21%)
• Similarity: 57/198 - (28%)
• Gaps: 82/198 - (41%)

  Fly  1160 CEPAHGSTYSGSISHGNTSH-------------------RSGGGGSISGGAGGSSGGGGGGSSSL 1205
            |||:.|..|....  |.:.:                   .||.|.:..||:|.|.||.||.....
 Frog   277 CEPSDGMPYEEGA--GGSGYPQGPPLLPLDMQGNQLLVLPSGHGAAGQGGSGTSPGGEGGKIFLC 339

  Fly  1206 NAGDQLSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRRQMHNNGPKFGTASPQA 1270
            :.|   ..:||.          |:|.||.:                    ||.|...|.  .|..
 Frog   340 HCG---KAFSHK----------SMRDRHVN--------------------MHLNLRPFD--CPVC 369

  Fly  1271 VKKMLSLSESSKIRPHQPFVPRHGSTMAGVIP----------------PLHHMHAAHGFSTPSPG 1319
            .||.       |::.|   :..|..|..||.|                ..|..|........:.|
 Frog   370 GKKF-------KMKHH---LTEHMKTHTGVKPYECEVCAKKFMWRDSFMRHRGHCERRHRATAGG 424

  Fly  1320 GVV 1322
            |::
 Frog   425 GII 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDZ-GEF	NP_609012.2	CAP_ED	128..237	CDD:237999
		RasGEFN	279..400	CDD:214571
		PDZ_signaling	404..494	CDD:238492
		DegQ	<422..494	CDD:223343
		PDZ_GEF_RA	757..841	CDD:176380
		RasGEF	871..1050	CDD:279011
		Rhomboid_SP	1252..>1357	CDD:289371	18/87 (21%)
zbtb22	XP_002938727.2	BTB_POZ_ZBTB22_BING1	12..123	CDD:349519
		C2H2 Zn finger	339..358	CDD:275368	7/51 (14%)
		zf-H2C2_2	352..374	CDD:372612	9/50 (18%)
		zf-C2H2	364..386	CDD:333835	7/33 (21%)
		C2H2 Zn finger	366..386	CDD:275368	6/29 (21%)
		zf-H2C2_2	378..401	CDD:372612	6/25 (24%)
		C2H2 Zn finger	394..418	CDD:275368	2/23 (9%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910