Protein Alignment CG13991 and CFAP100

DIOPT Version :9

• Sequence 1: NP_609000.2
• Gene: CG13991 / 33868
• FlyBaseID: FBgn0031785
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: NP_872434.2
• Gene: CFAP100 / 348807
• HGNCID: 26842
• Length: 611
• Species: Homo sapiens
• Alignment Length: 827
• Identity: 156/827 - (18%)
• Similarity: 266/827 - (32%)
• Gaps: 278/827 - (33%)

  Fly   131 SSSNSHFRDGIETVKLRKSVCSTTSTAKKSQSDSGQNGGSIRESSEKEPDSDELVDSMHLPSTRP 195
            |.:.::.::.:|::.:..|  |:|....|.|:         |::.|..||          ||..|
Human    10 SKNMTNDKNSLESMNISSS--SSTEENPKKQA---------RKNEEHGPD----------PSANP 53

  Fly   196 PHFKGEEWRRPCPASFVAGAPRPRIGRCPKNYEQLAKLTPARQKFFLTQDPRKTHCLVNPVALRH 260
            .|..|:                                    ..|||.:|..:...|..  ..:.
Human    54 FHLSGD------------------------------------VDFFLLRDQERNKALSE--RQQQ 80

  Fly   261 KPLTKEQEFSLISKLVKHGDNLCASTASETSDTHICEVIDLQNPLRLDFHGMDYKTTYEQDEVEQ 325
            |.:...|:.:..||:          :|..||         |:..|:|:....|.:.   :.|.|.
Human    81 KTMRVHQKMTYSSKV----------SAKHTS---------LRRQLQLEDKQEDLEA---RAEAEH 123

  Fly   326 QNAL---TFWRVQRYMARRKAKKNTKVNVEAELKEERLAVPQRYNTTIKDTPIETPSPPPSPRLV 387
            |.|.   |.|:    :...|.|.....|:...:|::|.....:|...:|...|:        ||.
Human   124 QRAFRDYTTWK----LTLTKEKNVEPENMSGYIKQKRQMFLLQYALDVKRREIQ--------RLE 176

  Fly   388 HLYRSPDKPANKLKIEEERRRRAARYKDIYLRKKQREEEQLLERRKQEAAIK-----EIEGRTVA 447
            .|   ..|...:|:..|:...:.|...|.::|:......|.:...::|...|     ||...|..
Human   177 TL---ATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETKAKIEKILEIRDLTTQ 238

  Fly   448 EADLRADVAVIDDAIERSFRKHVEL-KPIIRKRKVFPKTLTETERLKAIMHREDCVRRDKARVTQ 511
            ..:::::::..:|.:     ||.:: |..:  .|:.||...|
Human   239 IVNIKSEISRFEDTL-----KHYKVYKDFL--YKLSPKEWLE----------------------- 273

  Fly   512 QFYLERTGKHKYMPDAEQQLACDESIEGSVGSTPSEQSSDDEDYLQVGKIGDKFQLRGFHFKHGD 576
                |:..||.::..|::  ..:.|.|.||.|||                |||          |.
Human   274 ----EQEKKHSFLKKAKE--VSEASKESSVNSTP----------------GDK----------GP 306

  Fly   577 GLRGKLHRHQIMQGQRTVKGCLTREDW--LNQLVPHKEPIKLDV--------------ERGIIKV 625
            |::||.......:||.      |::.|  |..:...:.|..|..              .||....
Human   307 GIKGKASSMWAKEGQG------TKKPWRFLQTMRLGRSPSYLSSPQQGSQPSESSGGDSRGSNSP 365

  Fly   626 LDPDDPNLDLFPPEPLLVRRRERQ--SAVREFVHQKLGL-HYHRRLRKNLKIVKPKPAYNVRKFN 687
            :.|...:.|....||.|.....:|  ...||...|.|.| ...:...|.|:.:.     :..|..
Human   366 IPPTQEDTDSDGEEPQLYFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELS-----HTLKHT 425

  Fly   688 LIRYVFPEKVLVPDDRIPVEEME------VLDATKVNTTLEYLDMKQQL-----AKSKRQKKKLA 741
            .||.          || .|.:::      ::..||...|...|::|.::     .|..:|.|.|.
Human   426 QIRM----------DR-EVNQLKQWVTTMMMSITKEEDTAAELELKARVFHFGEYKGDQQDKLLE 479

  Fly   742 RMQLLGLP----CIEKEQ---LRAADPCLEVEEELD-----VDWVPTPEPPYNEGEGQSRQEGGC 794
            .:....|.    |...:|   |........:|.:||     ::.|  |:....:.|....:|
Human   480 SLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHV--PQVKIEQAERAKEKE--- 539

  Fly   795 DRPPRGPWKPTQFLVPENARNADLSGSSGLQCATSGQEGTAMERFPGGKESQPSRWRGNMPAPKE 859
                               |...|.           :|...|::....:..|.:|.|......|:
Human   540 -------------------RRIRLR-----------EEKLQMQKILQEEHLQRARARAQAEIKKK 574

  Fly   860 REKTLTIHPRRKRDYAAERVPSAIFNEVLQNSALPLLEQPEPEKLRF 906
            |.:||....|          |.|  :.:.|.|...|:::.|.|.|.|
Human   575 RGRTLVCRSR----------PPA--HRIKQQSEHTLMDKEEEELLFF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13991	NP_609000.2	None
CFAP100	NP_872434.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..57		15/67 (22%)
		DUF4200	151..269	CDD:290574	25/135 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..323		16/69 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..380		6/41 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JZ3
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900