DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and SNF1

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_010765.3	Gene:	SNF1 / 852088	SGDID:	S000002885	Length:	633	Species:	Saccharomyces cerevisiae

Alignment Length:	278	Identity:	98/278 - (35%)
Similarity:	162/278 - (58%)	Gaps:	19/278 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SKPQKTILEEHGIILG-----KVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPR 123
            :.|:.::.:  |..:|     |.:|.|::.|||:.:....|::||:|||:|........|..:.|
Yeast    40 NNPKSSLAD--GAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIER 102

  Fly   124 EIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVE 188
            ||..::.|.|.::|..|..|::...:.::::.|.| .|.||:.:|..:.|.::|..|:|::||||
Yeast   103 EISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIISAVE 166

  Fly   189 YIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGV 253
            |.|...:||||:|.|||||||:.|:|:.|||.:  :..|..|   ..||.|||..||:||::.|.
Yeast   167 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS--NIMTDGN---FLKTSCGSPNYAAPEVISGK 226

  Fly   254 AYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSL-VFPK--SPSASSECKHMIMHIL 315
            .|.....|:|:|||:.|.|:..|||:|..::.:|.|.|:..: ..||  ||.|:...|.|:  |:
Yeast   227 LYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRML--IV 289

  Fly   316 APVKIRYNIPQVKEDPWY 333
            .|:. |.:|.::.:|.|:
Yeast   290 NPLN-RISIHEIMQDDWF 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	96/265 (36%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	95/261 (36%)
SNF1	NP_010765.3	STKc_AMPK_alpha	52..306	CDD:270981	95/262 (36%)
		UBA_2	344..389	CDD:400760
		AdenylateSensor	504..626	CDD:406881
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910