DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and TSSK1B

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_114417.1	Gene:	TSSK1B / 83942	HGNCID:	14968	Length:	367	Species:	Homo sapiens

Alignment Length:	273	Identity:	123/273 - (45%)
Similarity:	181/273 - (66%)	Gaps:	11/273 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 ILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREIEAVKGLHHE 134
            :|:..|.:||..:|.|:|||||..:||.....||:|||.:.|||:::.:||||||||.:..|:|.
Human     6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHC 70

  Fly   135 NLITFYQSIETSH-RVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHR 198
            ::|..|:..|||| :||::|:||..|.||:.::.|..|.|.::|..|.||..|::|.|...||||
Human    71 SIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHR 135

  Fly   199 DIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVAYDPFMSDIW 263
            |:||:|||||:::|:||.||.|:::..|....::.||||||||.|||:||:|:|:.|.|.:.|||
Human   136 DLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIW 200

  Fly   264 ACGVVCYAMVFGRLPYDGSNVHILLK-----RINQSLVFPKSPSASSECKHMIMHILAP-VKIRY 322
            :.||:.|.||.|.:|||.||:..:|:     |:|    ||:|...:.|||.:|.|:|.| |..|.
Human   201 SLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVN----FPRSKHLTGECKDLIYHMLQPDVNRRL 261

  Fly   323 NIPQVKEDPWYSP 335
            :|.::....|..|
Human   262 HIDEILSHCWMQP 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	120/264 (45%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	119/260 (46%)
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	120/265 (45%)
TSSK1B	NP_114417.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	233	1.000	Domainoid score	I2402
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3315
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D403296at33208
OrthoFinder	1	1.000	-	-		FOG0007569
OrthoInspector	1	1.000	-	-		otm41276
orthoMCL	1	0.900	-	-		OOG6_103794
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X507
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.870