Protein Alignment CG9222 and NUAK2

DIOPT Version :10

• Sequence 1: NP_608999.2
• Gene: CG9222 / 33867
• FlyBaseID: FBgn0031784
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_112214.3
• Gene: NUAK2 / 81788
• HGNCID: 29558
• Length: 628
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 99/274 - (36%)
• Similarity: 146/274 - (53%)
• Gaps: 21/274 - (7%)

  Fly    47 PKPPAPSGVVPVKADDKSKPQKTILEE-------------HGIILGKVIGTGNYAKVKIGFSEEY 98
            |.|.|.....|: |:...|..|.::::             |.....:.:|.|.|.|||.. .|..
Human    12 PTPSAAELARPL-AEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKA-RESS 74

  Fly    99 GKRVAVKIISKVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLD 163
            |:.||:|.|.|.|...|.....:.||||.:..|:|.::|..::..|.|.::.::|:.|..|.|.|
Human    75 GRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYD 139

  Fly   164 YVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTS 228
            |:.||:.|.|.::|..|:|:||||.|.|...|||||:|.||:|||.|.|:|:.|||.:     ..
Human   140 YISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLS-----NL 199

  Fly   229 DNQVILSKTFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQ 293
            .:|....:|||||..||||||:.|..|.....|.|:.||:.|.:|.|.:|:||.:..||:|:|:.
Human   200 YHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISN 264

  Fly   294 SLVFPKSPSASSEC 307
            . .:.:.|..|..|
Human   265 G-AYREPPKPSDAC 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	91/233 (39%)
NUAK2	NP_112214.3	STKc_NUAK2	49..303	CDD:271063	92/236 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..493
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..562