DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and Nuak1

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001004363.1	Gene:	Nuak1 / 77976	MGIID:	1925226	Length:	658	Species:	Mus musculus

Alignment Length:	271	Identity:	101/271 - (37%)
Similarity:	150/271 - (55%)	Gaps:	21/271 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KPPAPSGVVPVKADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKA 112
            :|..|.||       |....|..| :|...|.:.:|.|.|.|||.......|:.||:|.|.|.|.
Mouse    36 EPRKPHGV-------KRHHHKHNL-KHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKI 92

  Fly   113 PSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSR 177
            ..|.....:.||||.:..|:|.::|:.|:..|...::.:||:.|..|.|.||:.||:.|.|.::|
Mouse    93 KDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETR 157

  Fly   178 TLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFA---RKDTRTSDNQVILSKTFC 239
            ..|:|:||||.|.|..||||||:|.||:|||:|.|:|:.|||.:   :||.        ..:|||
Mouse   158 HFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDK--------FLQTFC 214

  Fly   240 GSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSAS 304
            ||..||||||:.|..|.....|.||.||:.|.:::|.:|:||.:...|:::|:....  :.|:..
Mouse   215 GSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEY--REPTQP 277

  Fly   305 SECKHMIMHIL 315
            |:.:.:|..:|
Mouse   278 SDARGLIRWML 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	93/244 (38%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	93/241 (39%)
Nuak1	NP_001004363.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53		7/24 (29%)
		STKc_NUAK	54..307	CDD:270975	94/245 (38%)
		S_TKc	56..307	CDD:214567	93/243 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	353..422
		GILK motif	400..403
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910