DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and Mark2

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_006230941.1	Gene:	Mark2 / 60328	RGDID:	708483	Length:	841	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	109/288 - (37%)
Similarity:	171/288 - (59%)	Gaps:	14/288 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KPPAPSGVVPVKADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKA 112
            ||.:.|.::..:....|..::..:..:.::  |.||.||:||||:......||.||||||.|.:.
  Rat    27 KPSSKSNMLRGRNSATSADEQPHIGNYRLL--KTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL 89

  Fly   113 PSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSR 177
            .|...|| |.||:..:|.|:|.|::..::.|||...:||:|:.|..|.:.||:.....:.|.::|
  Rat    90 NSSSLQK-LFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEAR 153

  Fly   178 TLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSY 242
            ..|:|:||||:|.|.|.:||||:|.||||||.:.|:|:.||||:.:  .|..|::   .|||||.
  Rat   154 AKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNE--FTFGNKL---DTFCGSP 213

  Fly   243 AYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSP-SASSE 306
            .||:||:.:|..||....|:|:.||:.|.:|.|.||:||.|:..|.:|:.:...  :.| ..|::
  Rat   214 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY--RIPFYMSTD 276

  Fly   307 CKHMIMH--ILAPVKIRYNIPQVKEDPW 332
            |::::..  ||.|.| |..:.|:.:|.|
  Rat   277 CENLLKKFLILNPSK-RGTLEQIMKDRW 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	105/261 (40%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	104/256 (41%)
Mark2	XP_006230941.1	STKc_MARK	52..304	CDD:270974	105/263 (40%)
		S_TKc	53..304	CDD:214567	105/262 (40%)
		UBA_MARK2	322..363	CDD:270589
		MARK2_C	742..840	CDD:213386
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910