DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9222 and Brsk1

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001120809.1	Gene:	Brsk1 / 499073	RGDID:	1563268	Length:	778	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	97/296 - (32%)
Similarity:	158/296 - (53%)	Gaps:	29/296 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PQPKPPAPSGVV-PVKADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIIS 108
            |.|.||..:..| |.:                  |.|.:|.|....||:|.....|::|||||::
  Rat    20 PHPHPPQHAQYVGPYR------------------LEKTLGKGQTGLVKLGVHCITGQKVAVKIVN 66

  Fly   109 KVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDE 173
            :.|.......| :.|||..:|.:.|.:::..:...|....:||:::....|.|.||:.::..|..
  Rat    67 REKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 130

  Fly   174 PQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTF 238
            .::|..|:|:|||:::.||..:.|||:|.|||||||..|:::.|||.|......|     |.:|.
  Rat   131 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS-----LLETS 190

  Fly   239 CGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSA 303
            |||..||.||::||..||...:|:|:|||:.:|::.|.||:|..|:..||:::.:. ||......
  Rat   191 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRG-VFHMPHFI 254

  Fly   304 SSECKHMI--MHILAPVKIRYNIPQVKEDPWYSPSK 337
            ..:|:.::  |..:.|.| |.::.|:::.|||...|
  Rat   255 PPDCQSLLRGMIEVEPEK-RLSLEQIQKHPWYLGGK 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	88/259 (34%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	87/255 (34%)
Brsk1	NP_001120809.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		4/8 (50%)
		STKc_BRSK1_2	32..285	CDD:270983	89/278 (32%)
		S_TKc	34..284	CDD:214567	87/275 (32%)
		UBA_BRSK	314..367	CDD:270525
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	719..778
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910