DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and AMPKalpha

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	103/291 - (35%)
Similarity:	163/291 - (56%)	Gaps:	14/291 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PQPKPPAPSGVVPVKADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISK 109
            ||.:..|...|    |...:..|..:...| .:||..:|||.:.|||||..:....:|||||:::
  Fly     2 PQMRAAAAEAV----AAGSANGQPLVKIGH-YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNR 61

  Fly   110 VKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEP 174
            .|..|......:.|||:.:|...|.::|..||.|.|...:::||:....|.|.||:.:...|.|.
  Fly    62 QKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEH 126

  Fly   175 QSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFC 239
            |:|..|:|::|.|:|.|...:||||:|.||||||.|.::|:.|||.:   ....|.:.:  :|.|
  Fly   127 QARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLS---NMMLDGEFL--RTSC 186

  Fly   240 GSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSAS 304
            ||..||:||::.|..|.....|||:|||:.||::.|.||:|..:|..|.::| :|.:||.....:
  Fly   187 GSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKI-KSGIFPIPEYLN 250

  Fly   305 SECKHMIMHILA--PVKIRYNIPQVKEDPWY 333
            .:..:::..:|.  |:| |.||.::|:..|:
  Fly   251 KQVVNLVCQMLQVDPLK-RANIEEIKKHEWF 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	95/259 (37%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	95/255 (37%)
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	96/262 (37%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461623
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940