DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and Gm14147

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001365536.1	Gene:	Gm14147 / 381390	MGIID:	3651555	Length:	640	Species:	Mus musculus

Alignment Length:	277	Identity:	91/277 - (32%)
Similarity:	145/277 - (52%)	Gaps:	27/277 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 QKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREIEAVKGL 131
            ::..|.||..|| ..:|.|.:..||:........:||:||:     |.......:..|||.:|.|
Mouse    16 EEAALTEHYEIL-TTLGQGTFGDVKLANHLVTQTKVAIKIL-----PQNRKNPLVQPEIEIMKSL 74

  Fly   132 HHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVV 196
            .|.::|.....|:|:..::::::.|..|.|::.:.|..:|.|.:...||||||.|::|.|.||:|
Mouse    75 DHPHIIKLLHIIDTTRNIFIVLEHAVGGELMNRIEEFGYLAEVECHRLFKQLVYALQYCHEKGIV 139

  Fly   197 HRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSK---TFCGSYAYASPEILKGVAYDPF 258
            |||:|.||:|||...|:||.|||...|        :|:.:   ||||:..|.:||:.:...||..
Mouse   140 HRDLKPENILLDHRGNVKLTDFGLGTK--------IIMGQKLVTFCGTLPYCAPELFEDRGYDGR 196

  Fly   259 MSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLV---FPKSPSASSECKHMIMHILA--PV 318
            .:|:|:.|||.|.|..|.||::|.:    .:.|.|.::   :|:|.|.|.|...:|..:|.  |.
Mouse   197 ATDVWSLGVVLYFMATGCLPFNGYS----YEAIKQKIIAGKYPRSFSLSPELWEVIAKLLTVNPG 257

  Fly   319 KIRYNIPQVKEDPWYSP 335
            : |..:..:....|..|
Mouse   258 E-RPTVHDIARFKWLKP 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	86/265 (32%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	85/261 (33%)
Gm14147	NP_001365536.1	STKc_AMPK-like	23..270	CDD:270905	87/265 (33%)
Gm14147	NP_001365536.1	UBA_MARK_Par1	290..328	CDD:270522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910