DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and Sik3

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001188969.1	Gene:	Sik3 / 37152	FlyBaseID:	FBgn0262103	Length:	1471	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	115/298 - (38%)
Similarity:	162/298 - (54%)	Gaps:	21/298 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PQPKPPAPSGVVPVKADDKSKPQKTILEEHGII-LGKVIGTGNYAKVKIGFSEEYGKRVAVKIIS 108
            |...||..|.....|....||.....|...|.. |.|.||.||:|.||:..:.....:||:|||.
  Fly     9 PAAAPPTSSTPQNYKVPSTSKISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIID 73

  Fly   109 KVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDE 173
            |.....||..|.. |||..:|.|.|.::...|:.:|:...:||:.:.|.||.:.|::.....:.|
  Fly    74 KTCLNEEYLNKTF-REIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKE 137

  Fly   174 PQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFAR--KDTRTSDNQVILSK 236
            |::..:|.||||||.|.|.:||||||:|.||:|||::.|:||.||||:.  ::..|       .|
  Fly   138 PEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGAT-------LK 195

  Fly   237 TFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSP 301
            |:|||..||:||:.:|:.||...||||:.|||.||:|.|.||:||..:..|..|:    |..|..
  Fly   196 TWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRV----VLGKFR 256

  Fly   302 ---SASSECKHMI--MHILAPVKIRYNIPQVKEDPWYS 334
               ..|.||:.:|  |.::.|.: ||.|.|:.:..|.|
  Fly   257 IPFFMSQECEQLIRNMLVVEPDR-RYTIKQIIKHRWLS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	105/265 (40%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	104/260 (40%)
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	104/264 (39%)
		S_TKc	41..292	CDD:214567	104/263 (40%)
		UBA_SIK	335..380	CDD:270523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010