DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and Smok2a

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_038769.1	Gene:	Smok2a / 27263	MGIID:	1351487	Length:	504	Species:	Mus musculus

Alignment Length:	280	Identity:	97/280 - (34%)
Similarity:	153/280 - (54%)	Gaps:	27/280 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KSKPQKTILEEHGI---ILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPRE 124
            :|||..:.:|....   :|| .||.|...|||:......|..||||:|.|    .||..|.|..|
Mouse    13 RSKPPFSEMENFHAQYEMLG-TIGHGGSTKVKLARHRLTGTHVAVKMIPK----REYWCKPLMSE 72

  Fly   125 IEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEY 189
            .|.:....|.|:|:..|.|||..:|||||:|.|..:|..::|...:|.|.::|.|||||:||:.|
Mouse    73 AELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLLSAINY 137

  Fly   190 IHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVA 254
            .|::|:||||:|.:|::::::..:|:||||..   .:....|.:  ..|||:|.:::||:|....
Mouse   138 CHNQGIVHRDLKPDNIMVEKDGRVKIIDFGLG---IQVKPGQKL--NLFCGTYPFSAPEVLLSRP 197

  Fly   255 YDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSASSECK------HMIMH 313
            ||....|:|..|||.|.||.|::|:|.:::..|.|:|       .:...|..|:      |:|..
Mouse   198 YDGPKIDVWTLGVVLYFMVTGKIPFDAASIEKLRKQI-------VAGKYSVPCRLSVKLHHLITL 255

  Fly   314 ILAP-VKIRYNIPQVKEDPW 332
            ::.. .::|..:.:|...||
Mouse   256 LMTDNPELRPTVAEVMMHPW 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	93/268 (35%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	91/260 (35%)
Smok2a	NP_038769.1	STKc_AMPK-like	27..275	CDD:270905	91/264 (34%)
		S_TKc	28..276	CDD:214567	93/265 (35%)
		UBA_MARK_Par1	295..334	CDD:270522
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	376..403
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	443..469
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910