DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and aak-2

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_510710.2	Gene:	aak-2 / 181727	WormBaseID:	WBGene00020142	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	114/341 - (33%)
Similarity:	174/341 - (51%)	Gaps:	26/341 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKNDQGG------------VIGASSSQDLVTDQNSGRRQEQKVYTFSDRPPQPKPPAPSGVVPVK 59
            ||.|.||            ..|.:..::|....::..|:|:|....:|.  ..|..:|.|....|
Worm    11 RKEDGGGDGTEMKSKSRSQPSGLNRVKNLSRKLSAKSRKERKDRDSTDN--SSKMSSPGGETSTK 73

  Fly    60 ADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPRE 124
            ...:.|.|..|  .| .||.:.:|.|.:.|||:|..|....:|||||:::.|..|......:.||
Worm    74 QQQELKAQIKI--GH-YILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRRE 135

  Fly   125 IEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEY 189
            |:.:....|.::|..||.|.|...:::||:....|.|.||:.:...|...::|..|:|::|.|:|
Worm   136 IQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDY 200

  Fly   190 IHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVA 254
            .|...|||||:|.|||||||..|:|:.|||.:...|   |...:  :|.|||..||:||::.|..
Worm   201 CHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMT---DGDFL--RTSCGSPNYAAPEVISGKL 260

  Fly   255 YDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSPSASSECKHMIMHILA--P 317
            |.....|:|:|||:.||::.|.||:|..:|..|.::| :|.|||..........:::.|:|.  |
Worm   261 YAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKI-KSGVFPTPDFLERPIVNLLHHMLCVDP 324

  Fly   318 VKIRYNIPQVKEDPWY 333
            :| |..|..|....|:
Worm   325 MK-RATIKDVIAHEWF 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	94/259 (36%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	93/255 (36%)
aak-2	NP_510710.2	STKc_AMPK_alpha	84..339	CDD:270981	96/264 (36%)
		S_TKc	87..339	CDD:214567	94/258 (36%)
		UBA_AID_AMPKalpha	356..419	CDD:270521
		AMPKA_C	462..624	CDD:213378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910