DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and par-1

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001122967.2	Gene:	par-1 / 179912	WormBaseID:	WBGene00003916	Length:	1216	Species:	Caenorhabditis elegans

Alignment Length:	338	Identity:	113/338 - (33%)
Similarity:	182/338 - (53%)	Gaps:	25/338 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PRRKNDQGGVIGASSSQDLVTDQNSGRRQEQKVYTFSDRPPQPKPPAPSGVVPVKADDKSKPQKT 69
            |:||..:  |:..:.....:|  :||:|:..||....|.....:..:.|..........|.....
Worm    34 PKRKVSE--VVTTAPMAPTLT--SSGKRRTVKVSPDGDHVTHNRKNSSSHARSTGQSGMSSRSAA 94

  Fly    70 ILEEHGIILG-----KVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREIEAVK 129
            ...:..:.:|     |.||.||:||||:......|..||:|||.|........|| |.||::.:|
Worm    95 RRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQK-LFREVKIMK 158

  Fly   130 GLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKG 194
            .|.|.|::..||.:||...:||:::.|..|.:.||:.....:.|.::|..|:|:||||:|:|||.
Worm   159 QLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKN 223

  Fly   195 VVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVAYDPFM 259
            ::|||:|.||||||::.|:|:.||||:  :|.:..|::   .|||||..||:||:..|..||...
Worm   224 IIHRDLKAENLLLDQDMNIKIADFGFS--NTFSLGNKL---DTFCGSPPYAAPELFSGKKYDGPE 283

  Fly   260 SDIWACGVVCYAMVFGRLPYDGSNVHILLKRI---NQSLVFPKSPSASSECKHMIMHILA--PVK 319
            .|:|:.||:.|.:|.|.||:||.|:..|.:|:   ...:.|    ..|::|::::...|.  |.:
Worm   284 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLVINPQR 344

  Fly   320 IRYNIPQVKEDPW 332
             |.::..:.:|.|
Worm   345 -RSSLDNIMKDRW 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	100/268 (37%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	99/263 (38%)
par-1	NP_001122967.2	STKc_MARK	105..357	CDD:270974	99/263 (38%)
		S_TKc	106..357	CDD:214567	99/262 (38%)
		MARK1-3_C	1117..1214	CDD:213381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910