DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and prkaa1

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001120434.1	Gene:	prkaa1 / 100145520	XenbaseID:	XB-GENE-946195	Length:	551	Species:	Xenopus tropicalis

Alignment Length:	277	Identity:	104/277 - (37%)
Similarity:	160/277 - (57%)	Gaps:	11/277 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 ADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPRE 124
            |.||.|.....::....|||..:|.|.:.|||:|..|..|.:|||||:::.|..|......:.||
Frog     2 AADKQKHHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRRE 66

  Fly   125 IEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEY 189
            |:.:|...|.::|..||.|.|...::::|:....|.|.||:.:...|||.:||.||:|::|.|:|
Frog    67 IQNLKLFRHPHIIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQILSGVDY 131

  Fly   190 IHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVA 254
            .|...|||||:|.||:|||.:.|.|:.|||.:   ...:|.:.:  :|.|||..||:||::.|..
Frog   132 CHRHMVVHRDLKPENVLLDAHMNAKIADFGLS---NMMADGEFL--RTSCGSPNYAAPEVISGRL 191

  Fly   255 YDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVF-PK--SPSASSECKHMIMHILA 316
            |.....|||:|||:.||::.|.||:|..:|..|.|:|...:.: |:  :|...|..|||:  ::.
Frog   192 YAGPEVDIWSCGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPPVISLLKHML--LVD 254

  Fly   317 PVKIRYNIPQVKEDPWY 333
            |:| |..|..::|..|:
Frog   255 PMK-RATIKDIREHEWF 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	99/260 (38%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	98/256 (38%)
prkaa1	NP_001120434.1	STKc_AMPK_alpha	15..270	CDD:270981	99/262 (38%)
		S_TKc	18..270	CDD:214567	99/259 (38%)
		UBA_AID_AAPK1	287..351	CDD:270586
		AMPKA1_C	396..549	CDD:213384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910