DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9222 and mark2b

DIOPT Version :9

Sequence 1:	NP_608999.2	Gene:	CG9222 / 33867	FlyBaseID:	FBgn0031784	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_009301419.1	Gene:	mark2b / 100005996	ZFINID:	ZDB-GENE-080215-4	Length:	790	Species:	Danio rerio

Alignment Length:	340	Identity:	122/340 - (35%)
Similarity:	178/340 - (52%)	Gaps:	48/340 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATSPRRKNDQG-GVIGASSSQDLVTDQNSGRRQEQKVYTFSDRPPQPKPPAPSGVVPVKADDKS 64
            |:|.|     || .||..||||                 |.||.....:..||          :.
Zfish     1 MSTRP-----QGVAVIENSSSQ-----------------THSDAKGGVRSSAP----------RC 33

  Fly    65 KPQKTILEEHGII----LGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQKFLPREI 125
            :......||:..|    |.|.||.||:||||:.......|.||||||.|.:..|...||.. ||:
Zfish    34 RNAVATAEEYPHIGNYRLLKTIGKGNFAKVKLARHVLTSKEVAVKIIDKTQLNSSSLQKVF-REV 97

  Fly   126 EAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQSRTLFKQLVSAVEYI 190
            ..:|.|:|.|::..::.|||...:||:|:.|..|.:.||:.....:.|.::|..|:|:||||:|.
Zfish    98 RIMKLLNHPNIVKLFEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYC 162

  Fly   191 HSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVAY 255
            |.|.:||||:|.||||||.:.|:|:.||||:.:  .|..|::   .|||||..||:||:.:|..|
Zfish   163 HQKCIVHRDLKAENLLLDADMNIKIADFGFSNE--FTVGNKL---DTFCGSPPYAAPELFQGKKY 222

  Fly   256 DPFMSDIWACGVVCYAMVFGRLPYDGSNVHILLKRINQSLVFPKSP-SASSECKHMIMH--ILAP 317
            |....|:|:.||:.|.:|.|.||:||.|:..|.:|:.:...  :.| ..|::|::::..  ||.|
Zfish   223 DGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY--RIPFYMSTDCENLLKKFLILNP 285

  Fly   318 VKIRYNIPQVKEDPW 332
            .|......|:.:|.|
Zfish   286 TKRGSLEQQIMKDRW 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9222	NP_608999.2	STKc_TSSK4-like	75..333	CDD:271064	104/265 (39%)
CG9222	NP_608999.2	S_TKc	78..332	CDD:214567	102/256 (40%)
mark2b	XP_009301419.1	STKc_MARK	48..301	CDD:270974	103/261 (39%)
		S_TKc	49..301	CDD:214567	103/260 (40%)
		UBA_MARK2	319..360	CDD:270589
		AMPKA_C_like	691..789	CDD:302605
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910