Protein Alignment tctn and Tctn2

DIOPT Version :9

• Sequence 1: NP_608998.2
• Gene: tctn / 33866
• FlyBaseID: FBgn0261697
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001074251.1
• Gene: Tctn2 / 689779
• RGDID: 1591895
• Length: 700
• Species: Rattus norvegicus
• Alignment Length: 696
• Identity: 148/696 - (21%)
• Similarity: 228/696 - (32%)
• Gaps: 224/696 - (32%)

  Fly    22 IGISHNYNATISPTASTTTEAPA-TTGAPSSETVS-SISTLPEA---EVTT------------TT 69
            :|.|.:...:::|........|. |.|...:||.. :::..|:|   |||.            .|
  Rat    46 VGGSEDVTVSLTPLQIKEGVLPVPTCGGLRNETGDWNLTVSPQANMLEVTVRWKRGLDWCSPDET 110

  Fly    70 PAITFPPRVQQKPKVAVASPTMSTALPLNSTEVNSTLSVSGD---------NTFYY----CSCDL 121
            .:.:..|.:.|...|:.:......|..|...|:....||:.:         |..|.    |.|||
  Rat   111 ASFSEAPCIVQTLLVSASHNASCLAHLLIQVEIYPNTSVTHNASENMTVIPNQVYQPLGPCPCDL 175

  Fly   122 QAGRCDLNCCCDNDCPLETRQVFN--CLP----NSLLPQLESRLEDFQYTHGLPTCQINDGW--- 177
            .|..||:.||||.||..|.|::|.  |..    ..:.|....|.. .:.||..|      .|
  Rat   176 TAKACDIRCCCDQDCQPELRELFERFCFSGVFGGYVSPPSHHRCA-ARTTHQTP------DWFPF 233

  Fly   178 LCV------------FRSNTKATKTQPPDMNIDTSQYRKWKDNLEYQESDYAQSRP---SAGHYK 227
            |||            |.....:.:..|   ..:|..:...:|  .:.::.|.|..|   :.|::.
  Rat   234 LCVQSPPSTSPFLGHFYHGAISPRHSP---GFETHSHLDLRD--FFADASYKQGDPIMTTNGYFT 293

  Fly   228 F------GQTLQLWQPETKQLATLELPAAYESPNCQLKQSVWHLQPIRHVCRMKDSAQLQESIWS 286
            .      ||.||            :.|.|:             |:....||
  Rat   294 IPQASLAGQCLQ------------DAPVAF-------------LRNFHSVC-------------- 319

  Fly   287 LLNQTSNYEILSK----PRDLEEPEVNGLIVQVCLRGANKSMRCLERGNDTQLD--------VIV 339
                |::.|:..:    |.|:......||:...........:..|....||.|.        .:.
  Rat   320 ----TTDLEVQERDRLIPEDMRIRTTGGLVTPTVTYEEATDLDKLITSPDTILSAGSAPRNVTVE 380

  Fly   340 DHVELQLIHNFTNILEAKLFLEEAKLAEDDNEPLWLRYNVEFVTLNESLTKPTSGPLGYLSGAPV 404
            :|...:..:|..:.|:..:.  .|::.......:..|:.|:|::.|....|..||..||..|.||
  Rat   381 EHYVFRWQNNSISSLDITII--RAEINAHQRGTMTQRFTVKFLSPNSGGEKEFSGNPGYQLGKPV 443

  Fly   405 ILSRMLPQNSSEDKQLISYHSLNQNIKEFH-WLSLPSRKPRGSSCQRALDHKEALR---FGIDLL 465
               |.|             |:...|:...| |      :|.|    |.|....|||   ||.|..
  Rat   444 ---RAL-------------HTDGMNVTTLHLW------QPAG----RGLCTSAALRPVLFGEDAS 482

  Fly   466 TRCELRHAAPLLQAHANHTEYCQGLQAQIWSLLLPHNCTQL-EDVTK-----VFVSHLGR----- 519
            :.|       ||:.         |::         .||||| |:|.:     :..:|:.|
  Rat   483 SGC-------LLEV---------GIK---------ENCTQLRENVLQRLDLLIQATHVARRGNSD 522

  Fly   520 --PQPDKWLP-MEVRYPENVHEMPPPVQAVYDEMRQSLS-----CRNIFLSVGYEFHVAHLAMVE 576
              ...|.||. :.|..|:...::|             ||     |..:...|......|....||
  Rat   523 YGDLSDGWLEVIRVDAPDAGADLP-------------LSSANGMCPEVPTHVTIRILTAEAGAVE 574

  Fly   577 GRAPHQRVLQHARL--VLGQRH---DLEFDTSEIEVALPLSISAMF 617
            |.|..:.:....|.  |..|..   ..|.|.:::   ||||.|..|
  Rat   575 GEAQREILAVETRFSTVTWQYQCGLTCEEDKADL---LPLSASVKF 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tctn	NP_608998.2	DUF1619	117..403	CDD:285068	67/327 (20%)
Tctn2	NP_001074251.1	DUF1619	171..442	CDD:285068	67/327 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14611
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010