Protein Alignment tctn and Tctn3

DIOPT Version :9

• Sequence 1: NP_608998.2
• Gene: tctn / 33866
• FlyBaseID: FBgn0261697
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_003749157.1
• Gene: Tctn3 / 309486
• RGDID: 1305166
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 126/538 - (23%)
• Similarity: 199/538 - (36%)
• Gaps: 162/538 - (30%)

  Fly    34 PTASTTTEAPATTGAPSSETVSSISTLPEAEVTTTTPAITFPPRVQQKPKVAVASPTMST-ALPL 97
            |..|:|..|     .|:|..:..::    .||.||.     ||.:.:       |||..| ::|.
  Rat    26 PQPSSTARA-----LPTSWVLGPVT----PEVPTTA-----PPDLSE-------SPTPWTLSMPE 69

  Fly    98 N-STEVNSTLSVSGDNTFYYCSCDLQAGRCDLNCCCDNDCP-LETRQVFN-CLPNSLLPQLESRL 159
            | :|:....||:        |.|||..|.||||||||.||. |..|.||: |||.|:.
  Rat    70 NATTDPFPALSI--------CVCDLTPGTCDLNCCCDKDCDLLHPRTVFSFCLPGSVR------- 119

  Fly   160 EDFQYTHGLPTCQINDGWLC-----VFRSNTKATKTQPPDMNIDTSQYRKWKDNLEYQESDYAQ- 218
                          :..|:|     |||||:..    |..:..|:|...::...:...:|:|.|
  Rat   120 --------------SSSWVCVDNSLVFRSNSPF----PSRVFTDSSGITQFCVRVNNSKSNYFQE 166

  Fly   219 --------------------------SRPSAGHYKFGQTLQLWQPETKQLATLELPAAYESPN-C 256
                                      ::|....|:.|..:.::.|....::.|..|||..:.. |
  Rat   167 LQTVNATNFQALAAEFGGQFFTSTPKTQPPGPFYRAGDPILIYYPGLSVVSLLRQPAAVGAGGLC 231

  Fly   257 QLKQSVWHLQPIRHVCR--MKDSAQLQESIWS--LLNQTS--NYEILSKPRDLEEPEVNGLIVQV 315
            ........|:.....|.  .||   |..|..|  .|:..|  |:.:|..||.:  .::..:..||
  Rat   232 AESNPAGFLESKSTTCARFFKD---LTSSCTSEPALDAASYHNFRVLKVPRAM--TDLQSMKFQV 291

  Fly   316 CLRGANKSMRCLERGNDTQLDVIVDHVELQLIHNFT-NILEAKLFLEEAKLAEDDNEPLWLRYNV 379
            .:..|:::...|..||..|  .||..|..::..|.| .|.:..:...:..|.......|...:.:
  Rat   292 PVTLASQTSPPLLAGNTCQ--NIVSQVIYEIETNGTFGIQKVSVSFRQTNLTVKPGVSLQQDFII 354

  Fly   380 EFVTLNE----SLTKPTSGPLGYLSGAPVILSRMLPQNSSEDKQLISYHSLNQNIKEFHWLSLPS 440
            .|....:    |...|.||..|||:|.|::   :|..:.|....|:
  Rat   355 HFRAFQQREAASPAAPRSGNPGYLTGKPLL---VLTGDLSHSMTLL------------------- 397

  Fly   441 RKPRGSSCQRALDHKEALRFGIDLLTRCELRHAAPLLQAHANHTEYCQGLQAQIWSLLLPHNCTQ 505
             :..|:....|..|:  ::||::.::.|:||      ....|    |..||.:|:..|
  Rat   398 -QSEGNGLCSAKRHE--VQFGVNTVSGCQLR------PKEVN----CSHLQEEIYQTL------- 442

  Fly   506 LEDVTKVFVSHLGRPQPD 523
                      | |||:|:
  Rat   443 ----------H-GRPRPE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tctn	NP_608998.2	DUF1619	117..403	CDD:285068	82/331 (25%)
Tctn3	XP_003749157.1	DUF1619	82..382	CDD:285068	82/331 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10406
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I5288
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004997
OrthoInspector	1	1.000	-	-		oto98892
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14611
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.060