Protein Alignment tctn and Tctn1

DIOPT Version :10

• Sequence 1: NP_608998.2
• Gene: tctn / 33866
• FlyBaseID: FBgn0261697
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001388059.1
• Gene: Tctn1 / 304486
• RGDID: 1566266
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 132/628 - (21%)
• Similarity: 206/628 - (32%)
• Gaps: 199/628 - (31%)

  Fly     5 LPLVVLCLATYHTHSIKIGISHNYNATISPTASTT---------TEA-PATTGAPSSET-VSSIS 58
            ||.::|.|....|       |.:.....:|.|:|.         ||| |..|....:.| .:.:.
  Rat     6 LPPLLLVLLNCCT-------SSSTQVVATPAAATPVVTNEDLNFTEATPVVTNEDLNFTEATPVV 63

  Fly    59 TLPEAEVTTTTPAIT-----------------FPPRVQQKPKVAVASPTMSTALPLNSTEVNSTL 106
            |..:...|..||.:|                 :.||....|:    .|.:|...|...|:|.:
  Rat    64 TNEDLNFTEATPVVTNEDLNFTEATPATLRPSWSPRTPGTPR----PPELSGPRPTPVTDVAA-- 122

  Fly   107 SVSGDNTFYYCSCDLQAGRCDLNCCCDNDCPLETRQVFN-------------CLPNSLL------ 152
                     .|.|||...:||:|||||.||......||:             |...:..
  Rat   123 ---------LCVCDLLPAQCDINCCCDPDCSPGDFSVFSACSIPVVTGDRQFCSQKAAFYSMNLT 178

  Fly   153 ---PQLESRLEDFQYTHGLPTCQINDGWLCVFRSNTK-----ATKTQPPDMNIDTSQYRKWKDNL 209
               |..:.:|.|          |||....|:..||.|     |....|.:.|.|..........|
  Rat   179 ADPPHRDFKLID----------QINPSIFCIHISNYKPALSFANPEVPDENNFDRLMGASGGFTL 233

  Fly   210 EYQE---SDYAQSRPSAGHYKFGQTLQ-----------LWQPETKQLATLELPAAY---ESPNCQ 257
            ..:.   |......|....|::|..||           |..|.|..|...|.|||:   ::..|.
  Rat   234 SAESGVPSTATSDDPQPTKYEYGALLQTAGESSGSFLKLPSPLTSSLCADENPAAFLVNQAFECS 298

  Fly   258 LKQSVWHLQPIRHVCRMKDSAQLQESIWSLLNQTSNYEILSKPRDLEEP----EVNGLIVQVCLR 318
            .:.::             :..:..|::     ..::|   |.|..|..|    :|:..|..:..|
  Rat   299 RRVAI-------------EECERMEAL-----SMAHY---SSPAILRVPNSTTQVSIKIQSIMYR 342

  Fly   319 GANKSMRCLE-----------RGNDTQLDVIVDHVELQLIHNFT-NILEAKLFLEEAKLAEDDNE 371
            ..|.::..||           .|.|.....:|..|:..|::..: .|.||.|.|....|....:
  Rat   343 SLNHTLTQLEGRGILRPSLVSTGQDRLCSNVVLQVKYSLLYTASGQIQEAGLSLVLGTLISTVS- 406

  Fly   372 PLWLRYNVEFVTLNESLTKPT--SGPLGYLSGAPVILSRMLPQNSSEDKQLISYHSLNQNIKEFH 434
            .|..::.:.|:   :..|||.  ||..||..|.| :.:...||..|         .:.|......
  Rat   407 LLQQKFEIHFI---QHGTKPVPLSGNPGYRVGLP-LAAGFQPQKGS---------GIIQTTNRQG 458

  Fly   435 WLSLPSRKPRGSSCQRALDHKEALRFGIDLLTRCELRHAAPLLQAHANHTEYCQGLQAQIWSLLL 499
            .|:: .|......|..:...:..:.||.::.:.|:||         ...|..| ||.||
  Rat   459 QLTI-LRSTGKQDCLASHGQRAPVLFGYNVQSGCQLR---------LTGTIPC-GLLAQ------ 506

  Fly   500 PHNCTQLEDVTKVFVSHLGRPQPD--------------KWLPM 528
                 :::|:.:      |:..||              .|:|:
  Rat   507 -----KMQDLLR------GQAFPDYVAAFGNSRAQDVQDWVPV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tctn	NP_608998.2	Herpes_BLLF1	<33..>112	CDD:282904	22/106 (21%)
		TCTN_DUF1619	117..403	CDD:462260	79/347 (23%)
Tctn1	NP_001388059.1	TCTN_DUF1619	124..437	CDD:462260	79/347 (23%)