Protein Alignment tctn and tctn1

DIOPT Version :9

• Sequence 1: NP_608998.2
• Gene: tctn / 33866
• FlyBaseID: FBgn0261697
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_009303412.1
• Gene: tctn1 / 100007222
• ZFINID: ZDB-GENE-081104-157
• Length: 534
• Species: Danio rerio
• Alignment Length: 667
• Identity: 124/667 - (18%)
• Similarity: 214/667 - (32%)
• Gaps: 233/667 - (34%)

  Fly    14 TYHTHSIKI---GISH--NY-----NAT---ISPTASTTTEAPATTGAPSSETVSSISTLPEAEV 65
            |..|.:|.|   .::|  ||     |.|   :||||       |...||:..|...::.||:
Zfish    22 TNTTQNINITLEDLNHTSNYRDEMLNITELGVSPTA-------ADLPAPTDRTPEYVTGLPD--- 76

  Fly    66 TTTTPAITFPPRVQQKPKVAVASPTMSTALPLNSTEVNSTLSVSGDNTFYYCSCDLQAGRCDLNC 130
                        :.:.||..:.....:||.|
Zfish    77 ------------LNESPKSPIPDSPQATAAP---------------------------------- 95

  Fly   131 CCDNDCPLETRQVFNCLPNSLLPQLESRLEDFQYTHGLPTCQINDGWLCVFRSNTKATKTQPPDM 195
                            :|.|.:|.             :|..:..:|.       :.||...|.|.
Zfish    96 ----------------IPVSGVPP-------------VPVTEDEEGL-------SFATPEVPTDQ 124

  Fly   196 NIDTSQYRKWKDNLEYQESDYAQSRPSAGHYKFGQTLQLWQPETKQLATLELPAAYESPNCQLKQ 260
            |.|:...|.     ....:...:|.|.   |::|..:|....| .||.....||:..:.:|....
Zfish   125 NADSVFGRS-----NVSSATDVRSLPG---YRYGDIIQTVNKE-GQLEFFTFPASAGTAHCLDSN 180

  Fly   261 SVWHLQPIRHVC-RMKDSAQLQESIWSL-LNQTSNYEILSKPRDLEEPEVNGLIVQVCLRGANKS 323
            ....|:.....| |..|.|:...::.:| |....|:.|.|...  :..:|.|:.|      |..:
Zfish   181 PAGFLKEQTSRCMRSFDLARDCTTLGTLSLGNYLNFSIRSGKN--QGAKVIGVEV------AAIT 237

  Fly   324 MRCLERGNDTQLDV---------------------IVDHVELQLIHN----FTNILEAKLFLEEA 363
            ::.||   .||:.|                     :|..|:...::|    ..|::.|  ||..|
Zfish   238 LQSLE---GTQMPVDPADSSSYFPMLLQSGDVCSNVVQQVKYAFVYNKAGEILNVMAA--FLLGA 297

  Fly   364 KLAEDDNEPLWLRYNVEFVTLNESLT-KPTSGPLGYLSGAPVILSRMLPQNSSEDKQLISYHSLN 427
              .::...|:...:.:.|:..|...| ...||..||:.|.|                |::.....
Zfish   298 --IKNVMVPIQQEFQIMFLQENSQTTGLKYSGNPGYVLGRP----------------LVAGTRTA 344

  Fly   428 QNIKEFHWLSLPSRKPRGS----------SCQRALDHKEALRFGIDLLTRCELRHAAPLLQAHAN 482
            ..|.:|       ..|:||          .|.|....:..:.|||:.::.|.|:
Zfish   345 NGIVQF-------ADPKGSLTTIQTSVDQDCLRGSSRRSPVLFGINTISGCTLK----------- 391

  Fly   483 HTEYCQGLQAQIWSLLLPHNCTQLEDVTKVFVSHLGRPQPDKWLPMEVRYPENVHEMPPPVQAVY 547
               ...|:           ||:|:.:|  :..:..|:..||.........|:|..:. .|:|
Zfish   392 ---LSDGV-----------NCSQVSEV--ILWALKGQSFPDHVASFGNSLPQNSLDW-VPIQ--- 436

  Fly   548 DEMRQSLSCRNIFLSVGYEFHV-----AHLAMVEGRAPHQRVLQHARLVLGQRHDLEFDTSEIEV 607
               .|::|......|:...:|:     .:.|::.   |..:::.....::.....|.|.||...:
Zfish   437 ---NQTISLGAQACSIPLSYHLEVKWTKYGALLN---PQAQIVSIMETIITNTSSLAFITSPGGL 495

  Fly   608 ALPLSISAMFYRMQTKA 624
             ||::.|..|..:...|
Zfish   496 -LPVTSSVSFVDVSASA 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tctn	NP_608998.2	DUF1619	117..403	CDD:285068	59/313 (19%)
tctn1	XP_009303412.1	DUF1619	<110..336	CDD:285068	55/256 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004997
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14611
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.010