DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment WDR79 and AT4G21520

DIOPT Version :9

Sequence 1:	NP_001285665.1	Gene:	WDR79 / 33865	FlyBaseID:	FBgn0031782	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_193883.2	Gene:	AT4G21520 / 828237	AraportID:	AT4G21520	Length:	425	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	118/367 - (32%)
Similarity:	183/367 - (49%)	Gaps:	36/367 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 HYTKGCYWSPDGTCLLVPVHLDGMHVIEMPSDLYSADT---VQPARSLTKLQSEVHVPEGGTVYD 244
            ::.||..|||||:|.|.....:.:.:..:|.|  ..|:   ..|........:.:.|.||.:|||
plant    52 NFLKGLKWSPDGSCFLASSEDNTLSLFHLPQD--GGDSNGYGVPVPEEDSYGASLLVNEGESVYD 114

  Fly   245 CVWYPHMNSLQPETCLWLATRQHEPIHMWDAFDGSLRCSYSGYDAVDEVMAAISLAFSHDGEQIY 309
            ..|||:|:...|.||::..:.:..|||:||:..|.|||:|..|||:||:.||.|:.|:.||.:|:
plant   115 FCWYPYMSVSDPLTCVFATSTRDHPIHLWDSTSGELRCTYRAYDAMDEITAAFSVGFNPDGTKIF 179

  Fly   310 AGYKRCIKIFDTSRPGRFCDDYPV--------KFAISCIAQTTAHPHTLTCGNWHGYIQHFDLRC 366
            |||...|::||..||||....|..        ...:|.:|.:..:...|..|:   |.|...:..
plant   180 AGYNSSIRVFDLHRPGRDFRQYSTLQKNKEGQAGILSTLAFSPTNSGMLAVGS---YGQTTGIYR 241

  Fly   367 SHKQGPLFTLGGHKGGITQLRYGEFGNGEWHLFSGARKCDKILQWDMRNYKQPLVELQRHVD-TN 430
            ......|:.|.|.:||:|.:::.:.||   :|::|.||...||.||:|...:.:.:|.|..: ||
plant   242 EDNMELLYVLHGQEGGVTHVQFSKDGN---YLYTGGRKDPYILCWDIRKSVEIVYKLYRATENTN 303

  Fly   431 QRIQFDLASDSNWLASGDTRGFVNVWDLKKYGDPSVLPLHSDCCNGVALNPAMPILATSSGQFHF 495
            ||:.||:......|.:|...|.|:::||:.....|.....||..|..:.:|.:|:.|||||...|
plant   304 QRVFFDIEPCGRHLGTGGQDGLVHMYDLQTGNWVSGYQAASDTVNAFSFHPYLPMAATSSGHRRF 368

  Fly   496 TDQSAQGDNVTLNGTETTELPAPADVNQNQKEVLYENAVVMW 537
               :...|:   :|.:..||...||          ||.|.:|
plant   369 ---AIPDDD---DGEDKNELQLKAD----------ENCVSLW 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
WDR79	NP_001285665.1	WD40	<273..490	CDD:330360	75/225 (33%)
		WD40 repeat	294..332	CDD:293791	17/37 (46%)
		WD40 repeat	337..377	CDD:293791	7/39 (18%)
		WD40 repeat	384..424	CDD:293791	12/39 (31%)
		WD40 repeat	433..466	CDD:293791	8/32 (25%)
AT4G21520	NP_193883.2	WD40	<45..363	CDD:225201	104/318 (33%)
		WD40 repeat	57..96	CDD:293791	11/40 (28%)
		WD40 repeat	113..158	CDD:293791	19/44 (43%)
		WD40 repeat	163..209	CDD:293791	18/45 (40%)
		WD40 repeat	216..252	CDD:293791	7/38 (18%)
		WD40 repeat	258..299	CDD:293791	14/43 (33%)
		WD40 repeat	347..379	CDD:293791	11/37 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2919
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9995
Inparanoid	1	1.050	183	1.000	Inparanoid score	I1435
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D934297at2759
OrthoFinder	1	1.000	-	-		FOG0005823
OrthoInspector	1	1.000	-	-		oto3490
orthoMCL	1	0.900	-	-		OOG6_102801
Panther	1	1.100	-	-	LDO	PTHR13211
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4799
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830