Protein Alignment CG9175 and SEC12

DIOPT Version :10

• Sequence 1: NP_608995.2
• Gene: CG9175 / 33862
• FlyBaseID: FBgn0031779
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_014423.1
• Gene: SEC12 / 855760
• SGDID: S000005309
• Length: 471
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 84/473 - (17%)
• Similarity: 148/473 - (31%)
• Gaps: 158/473 - (33%)

  Fly    15 VNFPLYAVDMLTSRHILVAGGGGSSKTGVANGFEIY----------ELYHNGSHFCAEEVLRHET 69
            |.:|.|....|.:..:|||||||....|:.|...:.          |.:|..|.|..|:.....|
Yeast    10 VGYPAYGAKFLNNDTLLVAGGGGEGNNGIPNKLTVLRVDPTKDTEKEQFHILSEFALEDNDDSPT 74

  Fly    70 GANVVMNFAVRNGGRRGYLCAGQEAHCQMYYVQPRVQSEEDGNGNGVGVGDGKPAPEERPHENGN 134
            ..:          ..:|.:..|    |               |.|...:..||
Yeast    75 AID----------ASKGIILVG----C---------------NENSTKITQGK------------ 98

  Fly   135 VRQRNAHSGVEPVANGHRPPLSTADILRQFR--RLHFDIQAADVIQTDFLKGAEPLQRVVRISGN 197
                         .|.|         ||:|:  :::..::....:..|....|:...::|.||..
Yeast    99 -------------GNKH---------LRKFKYDKVNDQLEFLTSVDFDASTNADDYTKLVYISRE 141

  Fly   198 GRL--MATGGTDGKLRVWTFPQMTLAAELAAHSKEIDDLDFSPDSKLIASISKDAQGLVWDLASG 260
            |.:  :|:......:|:.....:|...|:.... |:.||.||.|.|::|.|:..:..::..:...
Yeast   142 GTVAAIASSKVPAIMRIIDPSDLTEKFEIETRG-EVKDLHFSTDGKVVAYITGSSLEVISTVTGS 205

  Fly   261 QLQHKLQWKTPEGAKYLFKRCRYGTVEAQKDNYRLFTIANPLGK--------------------- 304
            .:..|..:.         |......:....|:..|...:...||
Yeast   206 CIARKTDFD---------KNWSLSKINFIADDTVLIAASLKKGKGIVLTKISIKSGNTSVLRSKQ 261

  Fly   305 -VGKQRGFLQHWDCASGQLRQAVAIDESLSSLAVRDDGRFVAVGTMFSGSVSMYIAFSLQRVLHI 368
             ..:.:|.........|:|....:.|.|::.:.::|                    .|:.::  .
Yeast   262 VTNRFKGITSMDVDMKGELAVLASNDNSIALVKLKD--------------------LSMSKI--F 304

  Fly   369 PHAHSMFVTGLQFLPITNEEGPPISSDTEAAVLSISVDNKVCIHSL--------SQRRTIPAWIA 425
            ..|||..:|.:           .||.|: ..|.|:|..|.:.|..|        |.::.|..:..
Yeast   305 KQAHSFAITEV-----------TISPDS-TYVASVSAANTIHIIKLPLNYANYTSMKQKISKFFT 357

  Fly   426 IVFLIVMIFAVFVLCSYI 443
            ...|||::       |||
Yeast   358 NFILIVLL-------SYI 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<169..383	CDD:441893	36/237 (15%)
		WD40 repeat	190..226	CDD:293791	8/37 (22%)
		WD40 repeat	231..267	CDD:293791	9/35 (26%)
		WD40 repeat	296..327	CDD:293791	5/52 (10%)
SEC12	NP_014423.1	WD40	<138..335	CDD:441893	40/240 (17%)
		WD40 repeat	177..212	CDD:293791	9/34 (26%)
		WD40 repeat	219..258	CDD:293791	4/38 (11%)
		WD40 repeat	270..305	CDD:293791	6/56 (11%)
		WD40 repeat	312..360	CDD:293791	12/59 (20%)
		WD40 repeat	368..431	CDD:293791	1/1 (100%)