Protein Alignment CG9175 and SED4

DIOPT Version :10

• Sequence 1: NP_608995.2
• Gene: CG9175 / 33862
• FlyBaseID: FBgn0031779
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_009993.1
• Gene: SED4 / 850431
• SGDID: S000000663
• Length: 1065
• Species: Saccharomyces cerevisiae
• Alignment Length: 549
• Identity: 107/549 - (19%)
• Similarity: 165/549 - (30%)
• Gaps: 194/549 - (35%)

  Fly    15 VNFPLYAVDMLTSRHILVAGGGGSSKTGVAN-------GFE------------------------ 48
            |.:|:|....:....:|||||||...:...|       .|:
Yeast    10 VGYPIYGAKFINEGTLLVAGGGGQFNSSFPNKITALKVNFQKKKHIRRFREITLDSIDDAPTSLD 74

  Fly    49 ---------IYELYHNGS-----HFCAEEVLRHE-------------TGANVVMNFAVRNGGRRG 86
                     ..||:::.|     |...:.|...|             |..:|...|...|.....
Yeast    75 CNNNLILVGCNELFNDSSMENVNHHLRKFVFEQEHLKFVASIDFNRTTDPSVFTKFVYINQRATV 139

  Fly    87 YLCAGQEAHCQMYYVQPRVQSE----EDGN--------GNGV-------------GVGDGKPAPE 126
            ...|..|....:..:.||..:|    |.|.        .||:             .|.||.....
Yeast   140 AAIASSEVPTVIRIIDPRNLTENYEIETGREVNDLHFAPNGILLSYITSNSLEVASVRDGNFVAR 204

  Fly   127 ERPHEN----GNVRQRNAHS-----------GVEPVANGHRPP----LSTADILRQFRRLHFD-- 170
            :...:.    .|:|..|.::           ||..:..|....    |.||..:       ||
Yeast   205 KTDFDKNLVLSNIRFLNDNTLLVAASLSNSDGVSLLKLGVSSKGVKILKTASFM-------FDLN 262

  Fly   171 -IQAADVIQTDFLKGAEPLQRVVRISGNGRLMATGGTDGKLRVWTFPQMTLAAELAAHSKEIDDL 234
             |.:.||         .|.::.|.:|.|..|:|....:....|...|::        |...|..:
Yeast   263 GITSMDV---------SPNKKFVALSSNDNLVAIVSVEKLKLVQLVPRV--------HESTITKV 310

  Fly   235 DFSPDSKLIASISKDAQGLVWDLASGQLQHKLQ--WK---------TPEGAKYL-FKRCRYG--- 284
            .|||||:.:||.|......|..| ||.....|:  ||         ...||..| :|...:|
Yeast   311 TFSPDSRYLASTSMGNTINVLKL-SGTSSSILRNIWKFFLNFVLLVVLAGAIQLGYKHNVHGFIY 374

  Fly   285 ---------------TVEAQKDNYRLFTIANPLGKVGKQRGFLQHWDCASGQLRQAVAIDESLSS 334
                           |::....:|  |||.:....:.:....:...|.||....:..:.|.|...
Yeast   375 KHAHDIYKSKFKENTTIDQGSSSY--FTINDDYRGITESADIISATDVASDIETEFSSFDTSTMR 437

  Fly   335 LAVRDDGRFVAVG--------------TMFSGSVSMYIAFSLQRVLHIPHAHSMFVTGLQFLPIT 385
            ....|:.:||.:.              :..|.|.|...:|..:.|.:.|...|.          |
Yeast   438 TTTEDEQKFVWISSSADSQFTSADIPTSASSSSSSSSSSFYEESVTNEPIVSSP----------T 492

  Fly   386 NEEGPPISSDTEAAVL--------SISVD 406
            :|...|::|.||..::        |.|:|
Yeast   493 SEITKPLASPTEPNIVEKPSLPLNSESID 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<169..383	CDD:441893	55/260 (21%)
		WD40 repeat	190..226	CDD:293791	7/35 (20%)
		WD40 repeat	231..267	CDD:293791	13/35 (37%)
		WD40 repeat	296..327	CDD:293791	6/30 (20%)
SED4	NP_009993.1	WD40	<142..335	CDD:441893	46/217 (21%)
		WD40 repeat	172..209	CDD:293791	5/36 (14%)
		WD40 repeat	214..253	CDD:293791	6/38 (16%)
		WD40 repeat	265..300	CDD:293791	9/43 (21%)