DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9175 and PHF1

DIOPT Version :9

Sequence 1:	NP_608995.2	Gene:	CG9175 / 33862	FlyBaseID:	FBgn0031779	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_566961.1	Gene:	PHF1 / 824384	AraportID:	AT3G52190	Length:	398	Species:	Arabidopsis thaliana

Alignment Length:	272	Identity:	66/272 - (24%)
Similarity:	116/272 - (42%)	Gaps:	56/272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 LQRVVRISGNGRLMATGGTDGKLRVWTFPQMTLAAELAAHSKEIDDLDFSPDSKLIASISKDAQG 252
            ||:.:..|.:|..:|.||.||.||:..:|.:::..:.....|.|.|:|||.||:.:|:.|.|...
plant   124 LQKCMAFSFDGSKLAVGGVDGCLRIMEWPNLSVILDEPKAHKSIRDMDFSLDSEFLATTSTDGSA 188

  Fly   253 LVWDLASGQLQHKLQWKTPEGAKYLFKRCRYGTVEAQKDNYR--LFTIA----NPLGKV-----G 306
            .:|....|.....|:....|.    .:.||:     .||..:  ||..|    .|:..|     .
plant   189 RIWKAEDGFPLSTLERSGDEN----IELCRF-----SKDGTKPFLFCAAQRGDTPMVNVYDISTW 244

  Fly   307 KQRGFLQHWDCASGQLRQAVAIDESLSSLAVRDDGRFVAVGTMFSGSVSMYIAFSLQ-----RVL 366
            |:.||        .:|.:..|     |::||..||:::|:|.. .|.||:....:::     :.|
plant   245 KKLGF--------KKLSRKTA-----STMAVSLDGKYIALGGK-DGDVSVAEVKTMEIYHYSKRL 295

  Fly   367 HIPHAHSMFVTGLQFLPITNEEGPPISSDTEAAVLSISVDNKVCIHSLSQRRTIPAWIAIVFLIV 431
            |:..:    :..|:|.|            :|..:|:.|.:....:..|:..:....| .|..|:.
plant   296 HLGQS----IASLEFCP------------SERVMLTTSSEWGEMVTKLTVPKEWKEW-QIYALLF 343

  Fly   432 MIFAVFVLCSYI 443
            .:|...|:.:|:
plant   344 CLFMASVIAAYV 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<190..>421	CDD:225201	58/246 (24%)
		WD40	190..>420	CDD:295369	58/245 (24%)
		WD40 repeat	190..226	CDD:293791	10/35 (29%)
		WD40 repeat	231..267	CDD:293791	12/35 (34%)
		WD40 repeat	296..327	CDD:293791	8/39 (21%)
PHF1	NP_566961.1	WD40 repeat	78..119	CDD:293791
		WD40	127..>318	CDD:421866	56/229 (24%)
		WD40 repeat	127..162	CDD:293791	10/34 (29%)
		WD40 repeat	168..204	CDD:293791	12/35 (34%)
		WD40 repeat	210..250	CDD:293791	12/52 (23%)
		WD40 repeat	258..294	CDD:293791	10/36 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0771
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I2456
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D828247at2759
OrthoFinder	1	1.000	-	-		FOG0004751
OrthoInspector	1	1.000	-	-		otm2484
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23284
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970