DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9175 and preb

DIOPT Version :9

Sequence 1:	NP_608995.2	Gene:	CG9175 / 33862	FlyBaseID:	FBgn0031779	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001001231.1	Gene:	preb / 407912	XenbaseID:	XB-GENE-6456920	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	438	Identity:	138/438 - (31%)
Similarity:	224/438 - (51%)	Gaps:	53/438 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FPLYAVDMLTSRHILV-AGGGGSSKTGVANGFEIYELYHNGSHFCAEEVLRHETGANVVMNFAVR 80
            ||||:|.:...|.::: |||||:||||:.|.....:|........|..:..|:|.:...||.|:.
Frog    15 FPLYSVRIDPIRGLIITAGGGGASKTGIKNAVHFLQLEQISGRLSASLLHSHDTESRATMNMALA 79

  Fly    81 NGGRRGYLCAGQEAHCQMYYVQPRVQSEEDGNGNGVGVGDGKPAPEERPHENGNVRQRNAHSGVE 145
            .    ..:.|||:::|  :.::.||.|:|:.       .|.|   ::...|..:...||..|...
Frog    80 G----DVIAAGQDSNC--HILRYRVLSQEER-------ADMK---KQEKAETNDRTSRNRKSSRV 128

  Fly   146 PVANGHRPPLSTADILRQFRRLHFDIQAADVIQTDFLKGAEPLQRVVRISGNGRLMATGGTDGKL 210
            .:..|.|   .|.|     ......|:....:|||  ..|:.||:.|..:.:...:.|||.||.|
Frog   129 SIDGGIR---GTKD-----ETPEVSIELLHTVQTD--TSADTLQKAVCFNPDCTKLLTGGVDGYL 183

  Fly   211 RVWTFPQMTLAAELAAHSKEIDDLDFSPDSKLIASISKDAQGLVWDLASGQLQHKLQW-----KT 270
            |||.||.|....:..||:.||:|:..||.:|:: |:.:|.:..||:  :.||..:|.|     ..
Frog   184 RVWEFPGMKKLLDFKAHNGEIEDIASSPGNKMV-SVGQDFRCCVWE--ADQLLMELHWNENLPSI 245

  Fly   271 PEGAKYLFKRCRYGTVEAQKDNYRLFTIANPLGKVGKQRG---FLQHWDCASGQLRQAVAI---- 328
            |: ..|.::.||:|.|..|:|...|:|:..|..:  ::|.   :|..||    .||....:
Frog   246 PD-KMYRYRACRFGKVPDQQDALCLYTVQIPYKR--ERRPPPCYLTKWD----GLRFLPLVTQPC 303

  Fly   329 -DESLSSLAVRDDGRFVAVGTMFSGSVSMYIAFSLQRVLHIPHAHSMFVTGLQFLPITNEEGPPI 392
             :|.:|.|||.|.|:|:.:||: :|||::||:|||||:.::..||.:.||.|.|.| .:.....:
Frog   304 GNEVISCLAVSDCGKFLGLGTV-TGSVAIYISFSLQRLYYVEEAHGIVVTDLAFFP-GSRRCRDL 366

  Fly   393 SSDTEAAVLSISVDNKVCIHSLSQRRTIPAWIAIVF-LIVMIFAVFVL 439
            ..|.|.|:||::||::..:|.:..|||.|.|:.::. .|.::..||:|
Frog   367 QGDHETALLSVAVDSRCKLHLVPNRRTFPVWLLLLLCFISVVLVVFLL 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<190..>421	CDD:225201	84/243 (35%)
		WD40	190..>420	CDD:295369	83/242 (34%)
		WD40 repeat	190..226	CDD:293791	13/35 (37%)
		WD40 repeat	231..267	CDD:293791	11/35 (31%)
		WD40 repeat	296..327	CDD:293791	8/33 (24%)
preb	NP_001001231.1	WD40 repeat	17..68	CDD:293791	17/50 (34%)
		WD40 repeat	74..109	CDD:293791	13/50 (26%)
		WD40 repeat	161..196	CDD:293791	15/34 (44%)
		WD40	164..>385	CDD:330360	80/232 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6391
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40877
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4420
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D356175at33208
OrthoFinder	1	1.000	-	-		FOG0004751
OrthoInspector	1	1.000	-	-		oto103766
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5093
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060