DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9175 and tup11

DIOPT Version :9

Sequence 1:	NP_608995.2	Gene:	CG9175 / 33862	FlyBaseID:	FBgn0031779	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_592873.1	Gene:	tup11 / 2542299	PomBaseID:	SPAC18B11.10	Length:	614	Species:	Schizosaccharomyces pombe

Alignment Length:	264	Identity:	47/264 - (17%)
Similarity:	94/264 - (35%)	Gaps:	95/264 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 FDIQAADVIQTDFLKGAEPLQ----RVVRISGNGRLMATGGTDGKLRVWTFPQMTLAAELAAHSK 229
            ||:|....:.|...:..:|.:    |.:..|.:|:.:.||..|.::::|......:....:.|.:
pombe   339 FDVQTGKKLFTLHEESPDPSRDLYVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQ 403

  Fly   230 EIDDLDFSPDSKLIASISKDAQGLVWDLASGQLQHKLQWKTPEGAKYLFKRCRYGTVEAQKDNYR 294
            :|..||||.:.:.|.|.|.|....:||:.:||...||:
pombe   404 DIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLE--------------------------- 441

  Fly   295 LFTIANPLGKVGKQRGFLQHWDCASGQLRQAVAIDESLSSLAVRDDGRFVAVGTM--------FS 351
                                             |:..::::|:..:.:|:|||::        .|
pombe   442 ---------------------------------IENGVTAIAISPNDQFIAVGSLDQIIRVWSVS 473

  Fly   352 GSVSMYIAFSLQRVLHIPHAHSMFVTGLQFLPITNEEGPPISSDTEAAVLSISVDNKVCIHSLSQ 416
            |::       ::|:    ..|...|..:.|.|            ..:.:||.|:|..:.:..|..
pombe   474 GTL-------VERL----EGHKESVYSIAFSP------------DSSILLSGSLDKTIKVWELQA 515

  Fly   417 RRTI 420
            .|::
pombe   516 TRSV 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<190..>421	CDD:225201	42/239 (18%)
		WD40	190..>420	CDD:295369	42/237 (18%)
		WD40 repeat	190..226	CDD:293791	7/35 (20%)
		WD40 repeat	231..267	CDD:293791	14/35 (40%)
		WD40 repeat	296..327	CDD:293791	0/30 (0%)
tup11	NP_592873.1	Tup_N	9..86	CDD:285748
		WD40	<303..610	CDD:225201	47/264 (18%)
		WD40	306..608	CDD:238121	47/264 (18%)
		WD40 repeat	316..358	CDD:293791	4/18 (22%)
		WD40 repeat	364..400	CDD:293791	7/35 (20%)
		WD40 repeat	405..441	CDD:293791	14/35 (40%)
		WD40 repeat	447..481	CDD:293791	8/44 (18%)
		WD40 repeat	487..535	CDD:293791	9/45 (20%)
		WD40 repeat	541..577	CDD:293791
		WD40 repeat	583..607	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910