Protein Alignment CG9175 and sec-12

DIOPT Version :10

• Sequence 1: NP_608995.2
• Gene: CG9175 / 33862
• FlyBaseID: FBgn0031779
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_492305.2
• Gene: sec-12 / 172641
• WormBaseID: WBGene00010496
• Length: 425
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 135/465 - (29%)
• Similarity: 209/465 - (44%)
• Gaps: 104/465 - (22%)

  Fly    11 LLARVNFPLYAVDMLTSRHILVAGGGGSSKTGVANGFEIYELYHNGS-----HFCAEEVLRHETG 70
            |:.....|.|.:..:.|||||||||||:|||||.|..:.: |:..||     .|.::.|.:.:||
 Worm    14 LIGESGIPAYCLKTIGSRHILVAGGGGASKTGVLNEIQTH-LFTTGSANQDVGFQSKCVGKFDTG 77

  Fly    71 ANVVMNFAVRNG----GRRGYLCAGQEAHCQMYYVQPRVQSEEDGNGNGVGVGDGKPAPEERPHE 131
            :...||..|...    ..:..:.||||..|.:|..:....:||:
 Worm    78 SMATMNMDVACAFDEISAKYVIAAGQENLCALYMTRAFKLNEEN--------------------- 121

  Fly   132 NGNVRQRNAHSGVEPVANGHRPPLSTADILRQFRRLHFDIQAADVIQTDFLKGAEPLQRVVRI-- 194
                                             ..|.|:||....:::|| ..:...|:.||.
 Worm   122 ---------------------------------ECLSFEIQKVSQVRSDF-HASNSYQKCVRFDK 152

  Fly   195 SGNGRLMATGGTDGKLRVWTFPQMTLAAE---------LAAHSKEIDDLDFSPDSKLIASISKDA 250
            |..|::.||||.||.:|:|. .|:...||         :.||..::||:|||.|||.|.|:.  |
 Worm   153 SSRGKIFATGGADGHIRIWN-AQIVFRAENEDAQPILTIQAHKADVDDIDFSKDSKTIISVG--A 214

  Fly   251 QG-LVWDLASGQLQHKLQW--KTPEGAKYLFKRCRYGTVEAQKDNYRLFTIA-NPLGKVGK-QRG 310
            :| .:|...:|.....||:  :...|.|....||   |...:..|..:|..| |.:.|..| |..
 Worm   215 EGAFIWSTQTGARLLDLQFPIEISRGFKMRSIRC---TPLGKASNNTVFVAAYNSISKGSKDQAS 276

  Fly   311 FLQHW------DCASGQLRQAVAIDESLSSLAVRDDGRFVAVGTMFSGSVSMYIAFSLQRVLHIP 369
            ||..|      :.|...:.:.:|..:|:|||||.|.|.|.||||| ||||.::.....:|:...|
 Worm   277 FLSLWAFNSERNVARPVVTKLLAKGQSISSLAVSDCGNFTAVGTM-SGSVLVFDTHECRRLYFSP 340

  Fly   370 HAHSMFVTGLQFLPITN--------EEGPPISSDTEAAVLSISVDNKVCIHSL--SQRRTIPAWI 424
            .:|.:||||::|:..|:        .|.|.|:|..::||::::.|..:.:|.:  .|.:....::
 Worm   341 ESHGLFVTGIEFVSRTSPSICEDIQSETPGIASGFQSAVVTLAADKTMQLHRVPYPQPQPFSEYL 405

  Fly   425 AIVFLIVMIF 434
            .|:.|:.:||
 Worm   406 LIISLVCLIF 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9175	NP_608995.2	WD40	<169..383	CDD:441893	82/235 (35%)
		WD40 repeat	190..226	CDD:293791	15/46 (33%)
		WD40 repeat	231..267	CDD:293791	14/36 (39%)
		WD40 repeat	296..327	CDD:293791	10/38 (26%)
sec-12	NP_492305.2	WD40 repeat	146..192	CDD:293791	15/46 (33%)
		WD40	<147..352	CDD:441893	75/211 (36%)
		WD40 repeat	197..236	CDD:293791	16/40 (40%)
		WD40 repeat	244..284	CDD:293791	13/42 (31%)
		WD40 repeat	304..339	CDD:293791	18/35 (51%)