Protein Alignment Kr-h1 and ZNF764

DIOPT Version :10

• Sequence 1: NP_477466.1
• Gene: Kr-h1 / 33861
• FlyBaseID: FBgn0266450
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_219363.2
• Gene: ZNF764 / 92595
• HGNCID: 28200
• Length: 408
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 110/324 - (33%)
• Similarity: 148/324 - (45%)
• Gaps: 41/324 - (12%)

  Fly   171 VGGFPASAAVVSQVRK------PSASKPQF-KCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGAS 228
            :||  ...|::|.|.:      |:|..|:. ||          ...|....|.:|.::....|..
Human    67 IGG--NKPALISWVEEEAELWGPAAQDPEVAKC----------QTQTDPADSRNKKKERQREGTG 119

  Fly   229 GAGVAAPVSTAAIELN-----DAGLPVG---IPKS-----PTIKPLANVAAGADPYQCNVCQKTF 280
            ......||:..:..|.     .||.|.|   :.|:     |::.....|......:.|.||.|:|
Human   120 ALEKPDPVAAGSPGLKSPQAPSAGPPYGWEQLSKAPHRGRPSLCAHPPVPRADQRHGCYVCGKSF 184

  Fly   281 AVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRH 345
            |..:.|:.|..:||||:||.|..|.|.|....:|..||.||..|||::|..|||||.....|..|
Human   185 AWRSTLVEHVYSHTGEKPFHCTDCGKGFGHASSLSKHRAIHRGERPHRCLECGRAFTQRSALTSH 249

  Fly   346 MRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGE 410
            :|:||||:|:.|:.|.:.|.||..|..|.|.|:||.|:.||:  ||:.|.....|:.|.||||||
Human   250 LRVHTGEKPYGCADCGRRFSQSSALYQHRRVHSGETPFPCPD--CGRAFAYPSDLRRHVRTHTGE 312

  Fly   411 KPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAH-------IKGHANEV 467
            |||.|..|.|.|..:..:..||..|.|.|.|.|..|...|..|..:..|       ..||...|
Human   313 KPYPCPDCGRCFRQSSEMAAHRRTHSGEKPYPCPQCGRRFGQKSAVAKHQWVHRPGAGGHRGRV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	2/19 (11%)
		COG5048	<270..420	CDD:227381	70/149 (47%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368	9/19 (47%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..407	CDD:275368	8/21 (38%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		zf-C2H2	441..463	CDD:395048	6/28 (21%)
		C2H2 Zn finger	443..463	CDD:275368	5/26 (19%)
ZNF764	NP_219363.2	KRAB	26..85	CDD:214630	5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..167		16/85 (19%)
		C2H2 Zn finger	177..197	CDD:275368	8/19 (42%)
		zf-H2C2_2	190..212	CDD:463886	11/21 (52%)
		C2H2 Zn finger	205..225	CDD:275368	7/19 (37%)
		COG5048	229..>294	CDD:227381	31/66 (47%)
		C2H2 Zn finger	233..253	CDD:275368	9/19 (47%)
		C2H2 Zn finger	261..281	CDD:275368	8/19 (42%)
		C2H2 Zn finger	289..309	CDD:275368	8/21 (38%)
		zf-H2C2_2	301..326	CDD:463886	15/24 (63%)
		C2H2 Zn finger	317..337	CDD:275368	6/19 (32%)
		zf-H2C2_2	333..352	CDD:463886	8/18 (44%)
		C2H2 Zn finger	345..365	CDD:275368	5/19 (26%)