Protein Alignment Kr-h1 and ZNF835

DIOPT Version :10

• Sequence 1: NP_477466.1
• Gene: Kr-h1 / 33861
• FlyBaseID: FBgn0266450
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_001005850.2
• Gene: ZNF835 / 90485
• HGNCID: 34332
• Length: 537
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 149/537 - (27%)
• Similarity: 207/537 - (38%)
• Gaps: 104/537 - (19%)

  Fly    38 KAVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQFCLQVPPPLTATTTSVGLGVPPSGGQQE 102
            :|||.|..||.||             :.:.::.|:....:..|   .||..|    ||.....:.
Human    38 EAVACKGDPAGDS-------------MQERDEFSRIPRTISSP---AATQAS----VPDDSSSRR 82

  Fly   103 HFELLQTPQQRQMQLQLQDQHQQEQ-------------QQFVSYQLAIQQHQKQQQQQQHESITN 154
            .....::|::|.     .|..|:|:             .:..||..|...||:..        |.
Human    83 CSAPGESPKERH-----PDSRQRERGGGPKKPWKCGDCGKAFSYCSAFILHQRIH--------TG 134

  Fly   155 AAPTAAPSAQRIKTEPVGGFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKN 219
            ..|.|.|...:       .|..|..:....|..:..|| :.|.:||..|...|...||.::|:..
Human   135 EKPFACPECGK-------AFSQSVHLTLHQRTHTGEKP-YACHECGKAFSQGSYLASHWRTHTGE 191

  Fly   220 QDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTIKPLAN---------VAAGADPYQCNV 275
            :.........|.......|....::....|...  :...|...|         :..|..||:|:.
Human   192 KPHRCADCGKAFTRVTHLTQHRRVHTGERPYAC--AQCAKAFRNRSSLIEHQRIHTGEKPYECSA 254

  Fly   276 CQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSG 340
            |.|.|...:.||||.|.||.|:|:.|..|.|.|:...:|..|||:||.|:||.|..||..|..|.
Human   255 CAKAFRFSSALIRHQRIHTEEKPYRCGQCAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSA 319

  Fly   341 KLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPG---------------- 389
            .|..|.||||||:|:.|..|.|.|.|...|..|.||||||:||.|.:.|
Human   320 SLAEHRRIHTGEKPYACGQCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRLVH 384

  Fly   390 ----------CGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCT 444
                      ||..|:....|..|.:.||||:||.|..|.:.|.....|.||:..|.|.:.|.|.
Human   385 TGERPYRCLQCGAAFSHVSSLIEHQKIHTGERPYKCGECGKAFSQGSSLALHQRTHTGERPYTCP 449

  Fly   445 ICDETFKNKKEMEAHIKGHANEVPDDEAEAAAASAAAS-------TSAGSS-----AGSP-SLQG 496
            .|.:.|.|:..:..|...|..|.|.:.:....|.:.:|       |.|.||     |.:| |..|
Human   450 ECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKAFSFSSALIRHQRTHADSSGRLCPAPTPDSTPG 514

  Fly   497 VSSNSESSNHSPPSSPP 513
            :|...|:.....|...|
Human   515 LSQGGETCQQGCPGRNP 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	7/19 (37%)
		COG5048	<270..420	CDD:227381	72/175 (41%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..407	CDD:275368	7/47 (15%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		zf-C2H2	441..463	CDD:395048	6/21 (29%)
		C2H2 Zn finger	443..463	CDD:275368	5/19 (26%)
ZNF835	NP_001005850.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	12..109		20/95 (21%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		COG5048	136..487	CDD:227381	110/360 (31%)
		C2H2 Zn finger	140..160	CDD:275368	4/26 (15%)
		C2H2 Zn finger	168..188	CDD:275368	7/19 (37%)
		C2H2 Zn finger	196..216	CDD:275368	2/19 (11%)
		C2H2 Zn finger	224..244	CDD:275368	2/21 (10%)
		C2H2 Zn finger	252..272	CDD:275368	9/19 (47%)
		C2H2 Zn finger	280..300	CDD:275368	8/19 (42%)
		C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		C2H2 Zn finger	336..356	CDD:275368	8/19 (42%)
		C2H2 Zn finger	364..384	CDD:275368	2/19 (11%)
		C2H2 Zn finger	392..412	CDD:275368	5/19 (26%)
		C2H2 Zn finger	420..440	CDD:275368	6/19 (32%)
		C2H2 Zn finger	448..468	CDD:275368	5/19 (26%)
		C2H2 Zn finger	476..496	CDD:275368	2/19 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..537		11/35 (31%)