DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kr-h1 and STP3

DIOPT Version :9

Sequence 1:	NP_477466.1	Gene:	Kr-h1 / 33861	FlyBaseID:	FBgn0266450	Length:	845	Species:	Drosophila melanogaster
Sequence 2:	NP_013479.3	Gene:	STP3 / 851089	SGDID:	S000004367	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	348	Identity:	79/348 - (22%)
Similarity:	122/348 - (35%)	Gaps:	124/348 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 SITNAAPTAAPSAQRIK------TEPVGGFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSA- 208
            :|:|.:.:|..|:..:.      :..|....:|::.:..|::|              |.||.||
Yeast    48 NISNGSGSAGASSSMLSYQLLPHSNDVSRSNSSSSFLPSVQQP--------------TEGSASAS 98

  Fly   209 HTSHTKSHSKNQD--LSLNGAS---GAGVAAPVSTAAIELNDAGLPVGIPKSPTIKPLANVAAGA 268
            .||.:.|.|::..  |.:.|.|   ||||:.|.||   ::|              ||       .
Yeast    99 ETSSSASPSRSISPILKVAGPSSVGGAGVSTPHST---KIN--------------KP-------R 139

  Fly   269 DPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIH--TKERPYKCDV 331
            ...||.:|:..:|                               ||..|:..|  .::||:||.:
Yeast   140 KKKQCPICRNFYA-------------------------------NLTTHKATHLTPEDRPHKCPI 173

  Fly   332 CGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHM------------RTHTGEKPYK 384
            |.|.|..:..|.||.:.|..         ::...|||.|..|.            .||....|.
Yeast   174 CHRGFARNNDLLRHKKRHWK---------DEILSQSGVLSNHNDGKGGSVSPNDDDTHEKMTPM- 228

  Fly   385 CPEPGCGKGFTCSKQLK-VHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTI--- 445
                   ...|...||| :|....|.:.|::..:...|... :..||..:....|.|::..:
Yeast   229 -------NSVTDYAQLKSLHQIKGTFKCPFNSTLIQLDMDM-YPYKLKPLNFETSNCHQTGVFSR 285

  Fly   446 CDETFKNKKEMEAHIKGHANEVP 468
            || ||||      |:|....|.|
Yeast   286 CD-TFKN------HLKALHFEYP 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	7/20 (35%)
		COG5048	<270..420	CDD:227381	34/164 (21%)
		zf-C2H2	271..293	CDD:278523	4/21 (19%)
		C2H2 Zn finger	273..293	CDD:275368	3/19 (16%)
		zf-H2C2_2	286..309	CDD:290200	0/22 (0%)
		C2H2 Zn finger	301..321	CDD:275368	3/19 (16%)
		zf-H2C2_2	313..338	CDD:290200	11/26 (42%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		zf-H2C2_2	344..366	CDD:290200	3/21 (14%)
		C2H2 Zn finger	357..377	CDD:275368	5/31 (16%)
		zf-H2C2_2	370..396	CDD:290200	5/37 (14%)
		C2H2 Zn finger	385..407	CDD:275368	5/22 (23%)
		zf-H2C2_2	400..424	CDD:290200	6/24 (25%)
		C2H2 Zn finger	415..435	CDD:275368	3/19 (16%)
		zf-C2H2	441..463	CDD:278523	8/24 (33%)
		C2H2 Zn finger	443..463	CDD:275368	8/22 (36%)
STP3	NP_013479.3	COG5048	<137..295	CDD:227381	48/220 (22%)
		C2H2 Zn finger	144..161	CDD:275368	6/47 (13%)
		C2H2 Zn finger	171..191	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100