DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kr-h1 and SGR5

DIOPT Version :9

Sequence 1:	NP_477466.1	Gene:	Kr-h1 / 33861	FlyBaseID:	FBgn0266450	Length:	845	Species:	Drosophila melanogaster
Sequence 2:	NP_001077868.1	Gene:	SGR5 / 814725	AraportID:	AT2G01940	Length:	446	Species:	Arabidopsis thaliana

Alignment Length:	435	Identity:	87/435 - (20%)
Similarity:	150/435 - (34%)	Gaps:	112/435 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 KCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTIK 259
            :.||  :...:|:.:|....| |.:.|..|:.:.........||...:...||.|         .
plant     2 RTDQ--VMLSNKNTNTCCVVS-SSSSDPFLSSSENGVTTTNTSTQKRKRRPAGTP---------D 54

  Fly   260 PLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKE 324
            |.|.|.:              ..|..|:...|       :.||.|::.|...:|||:|||.|  :
plant    55 PDAEVVS--------------LSPRTLLESDR-------YICEICNQGFQRDQNLQMHRRRH--K 96

  Fly   325 RPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPG 389
            .|:|.            |.|...|...:|                            .|.||||.
plant    97 VPWKL------------LKRDNNIEVKKR----------------------------VYVCPEPT 121

  Fly   390 CGKGFTCSK-----QLKVH-SRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDE 448
            |.....|..     .:|.| .|.|:..|.:.|:.|.:.:......|.| ::..|::.:.   ||.
plant   122 CLHHNPCHALGDLVGIKKHFRRKHSNHKQWVCERCSKGYAVQSDYKAH-LKTCGTRGHS---CDC 182

  Fly   449 TFKNKKEMEAHIKGHAN--------EVPDDEAEAAAASAAASTSAGSSAGSPSLQGVSSNSESSN 505
            .|.:...:|:.|:...|        |.|.....|....|.:|.:|.:         ||:.|..:|
plant   183 GFFSSFRVESFIEHQDNCSARRVHREPPRPPQTAVTVPACSSRTAST---------VSTPSSETN 238

  Fly   506 HSPPSSPPATKKPRQAR--QPRVSKTVAATLSIPTSSPLSPSSLSSTYSPSASSMASPPPTSAHY 568
            :. .:....|.:|.:.|  ..|:|.::....|...:..|....|||..:|:..:........:|:
plant   239 YG-GTVAVTTPQPLEGRPIHQRISSSILTNSSNNLNLELQLLPLSSNQNPNQENQQQKVKEPSHH 302

  Fly   569 LPVQMEADALSRDSGVSSAQPAHSTY-------ADEEPTDLSMQQ 606
            .....:...|:.....||:...::.:       |.|:...::|::
plant   303 HNHNHDTTNLNLSIAPSSSYQHYNNFDRIKEIMASEQIMKIAMKE 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	4/19 (21%)
		COG5048	<270..420	CDD:227381	34/155 (22%)
		zf-C2H2	271..293	CDD:278523	3/21 (14%)
		C2H2 Zn finger	273..293	CDD:275368	3/19 (16%)
		zf-H2C2_2	286..309	CDD:290200	5/22 (23%)
		C2H2 Zn finger	301..321	CDD:275368	10/19 (53%)
		zf-H2C2_2	313..338	CDD:290200	9/24 (38%)
		C2H2 Zn finger	329..349	CDD:275368	2/19 (11%)
		zf-H2C2_2	344..366	CDD:290200	3/21 (14%)
		C2H2 Zn finger	357..377	CDD:275368	0/19 (0%)
		zf-H2C2_2	370..396	CDD:290200	6/25 (24%)
		C2H2 Zn finger	385..407	CDD:275368	9/27 (33%)
		zf-H2C2_2	400..424	CDD:290200	7/24 (29%)
		C2H2 Zn finger	415..435	CDD:275368	4/19 (21%)
		zf-C2H2	441..463	CDD:278523	5/21 (24%)
		C2H2 Zn finger	443..463	CDD:275368	5/19 (26%)
SGR5	NP_001077868.1	C2H2 Zn finger	75..95	CDD:275368	10/19 (53%)
		C2H2 Zn finger	117..145	CDD:275368	9/27 (33%)
		C2H2 Zn finger	153..172	CDD:275368	4/19 (21%)
		ATP-synt_B	<332..422	CDD:304375	3/16 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910