Protein Alignment Kr-h1 and ZNF665

DIOPT Version :10

• Sequence 1: NP_477466.1
• Gene: Kr-h1 / 33861
• FlyBaseID: FBgn0266450
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_001340387.1
• Gene: ZNF665 / 79788
• HGNCID: 25885
• Length: 706
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 124/344 - (36%)
• Similarity: 150/344 - (43%)
• Gaps: 81/344 - (23%)

  Fly   126 EQQQFVSYQLAIQQHQKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQVRK-PSA 189
            |.|..||:    |.|..:.||.|||                         ......:||.| |:.
Human   166 ENQLGVSF----QSHLPELQQFQHE-------------------------GKIYEYNQVEKSPNN 201

  Fly   190 SKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPK 254
            ....:|||:||..|...|..|||.:.|:
Human   202 RGKHYKCDECGKVFSQNSRLTSHKRIHT------------------------------------- 229

  Fly   255 SPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRR 319
                        |..|||||.|.|.|.|.:.|..|...||||:|::|..|.|:||...||..|:|
Human   230 ------------GEKPYQCNKCGKAFTVRSNLTIHQVIHTGEKPYKCNECGKVFSQPSNLAGHQR 282

  Fly   320 IHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYK 384
            |||.|:||||:.||:||....||..|..|||||:|:||..|.|.|.|:..|..|.|.||||||||
Human   283 IHTGEKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKECGKCFTQNSHLASHRRIHTGEKPYK 347

  Fly   385 CPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDET 449
            |.|  |||.|:....|..|...|||||||.|:.|.:.|.:|..|..||..|.|.|.|||..|.:.
Human   348 CNE--CGKAFSVRSSLTTHQTIHTGEKPYKCNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKA 410

  Fly   450 FKNKKEMEAHIKGHANEVP 468
            |.....:..|...|..|.|
Human   411 FSMHSNLTKHQIIHTGEKP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	9/19 (47%)
		COG5048	<270..420	CDD:227381	80/149 (54%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	9/19 (47%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..407	CDD:275368	8/21 (38%)
		C2H2 Zn finger	415..435	CDD:275368	7/19 (37%)
		zf-C2H2	441..463	CDD:395048	6/21 (29%)
		C2H2 Zn finger	443..463	CDD:275368	4/19 (21%)
ZNF665	NP_001340387.1	KRAB	37..76	CDD:460171
		COG5048	192..580	CDD:227381	113/289 (39%)
		C2H2 Zn finger	208..228	CDD:275368	9/19 (47%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		C2H2 Zn finger	264..284	CDD:275368	9/19 (47%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		C2H2 Zn finger	348..368	CDD:275368	8/21 (38%)
		C2H2 Zn finger	376..396	CDD:275368	7/19 (37%)
		C2H2 Zn finger	404..424	CDD:275368	4/19 (21%)
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		zf-H2C2_2	584..608	CDD:463886
		C2H2 Zn finger	600..620	CDD:275368
		zf-H2C2_2	612..637	CDD:463886
		C2H2 Zn finger	628..648	CDD:275368
		zf-H2C2_2	640..664	CDD:463886
		C2H2 Zn finger	656..676	CDD:275368
		zf-H2C2_2	669..693	CDD:463886
		C2H2 Zn finger	684..704	CDD:275368